1567335-34-5

Basic information

• Product Name: trifluoromethanesulfonic acid 2-(2-methoxyphenyl)-5-(2,2,6,6-tetramethyltetrahydropyran-4-yl)-2H-pyrazol-3-yl ester
• Synonyms: trifluoromethanesulfonic acid 2-(2-methoxyphenyl)-5-(2,2,6,6-tetramethyltetrahydropyran-4-yl)-2H-pyrazol-3-yl ester
• CAS NO: 1567335-34-5
• Molecular Weight: 462.49
• Mol File: 1567335-34-5.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: trifluoromethanesulfonic acid 2-(2-methoxyphenyl)-5-(2,2,6,6-tetramethyltetrahydropyran-4-yl)-2H-pyrazol-3-yl ester(CAS DataBase Reference)
• NIST Chemistry Reference: trifluoromethanesulfonic acid 2-(2-methoxyphenyl)-5-(2,2,6,6-tetramethyltetrahydropyran-4-yl)-2H-pyrazol-3-yl ester(1567335-34-5)
• EPA Substance Registry System: trifluoromethanesulfonic acid 2-(2-methoxyphenyl)-5-(2,2,6,6-tetramethyltetrahydropyran-4-yl)-2H-pyrazol-3-yl ester(1567335-34-5)

Safety Data

• Hazardous Substances Data: 1567335-34-5(Hazardous Substances Data)

Upstream product

• 1567335-33-4 2-(2-methoxyphenyl)-5-(2,2,6,6-tetramethyltetrahydropyran-4-yl)-2,4-dihydropyrazol-3-one 
• 98611-89-3 N-phenylbis(trifluoromethanesulfonyl)amine 
• 57396-67-5 (2-methoxyphenyl)hydrazine hydrochloride 
• 1429421-99-7 2,2,6,6-tetramethyltetrahydro-2H-pyran-4-carboxylic acid 
• 6971-45-5 2-methoxyphenylhydrazine hydrochloride 
• 37595-74-7 N,N-phenylbistrifluoromethane-sulfonimide 
• 1567335-32-3 3-oxo-3-(2,2,6,6-tetramethyltetrahydropyran-4-yl)thiopropionic acid S-phenyl ester 
• 1567335-31-2 benzotriazol-1-yl-(2,2,6,6-tetramethyltetrahydropyran-4-yl)methanone 
• 1197-66-6 2,2,6,6-tetramethyltetrahydropyran-4-one 

Downstream Products

• 1567335-35-6 2-(5-(4-chlorophenyl)-3-(2,2,6,6-tetramethyltetrahydro-2H-pyran-4-yl)-1H-pyrazol-1-yl)phenol 
• 1567334-74-0 1-(2-tert-butoxyphenyl)-5-(4-chlorophenyl)-3-(2,2,6,6-tetramethyltetrahydro-2H-pyran-4-yl)-1H-pyrazole 
• 1567335-29-8 5-(4-chlorophenyl)-1-(2-methoxyphenyl)-3-(2,2,6,6-tetramethyltetrahydropyran-4-yl)-1H-pyrazole 
• 1567335-76-5 5-(4-(benzyloxy)phenyl)-1-(2-methoxyphenyl)-3-(2,2,6,6-tetramethyltetrahydro-2H-pyran-4-yl)-1H-pyrazole 
• 1567334-37-5 5-(4-ethoxyphenyl)-1-(2-methoxyphenyl)-3-(2,2,6,6-tetramethyltetrahydro-2H-pyran-4-yl)-1H-pyrazole 
• 1567335-26-5 4-[1-(2-methoxyphenyl)-3-(2,2,6,6-tetramethyltetrahydro-2H-pyran-4-yl)-1H-pyrazol-5-yl]benzonitrile 
• 1567334-46-6 2-ethoxy-5-[1-(2-methoxyphenyl)-3-(2,2,6,6-tetramethyltetrahydro-2H-pyran-4-yl)-1H-pyrazol-5-yl]pyridine 
• 1567335-30-1 5-[1-(2-methoxyphenyl)-3-(2,2,6,6-tetramethyltetrahydro-2H-pyran-4-yl)-1H-pyrazol-5-yl]-2-methylpyridine 
• 1567334-50-2 2-chloro-4-[1-(2-methoxyphenyl)-3-(2,2,6,6-tetramethyltetrahydro-2H-pyran-4-yl)-1H-pyrazol-5-yl]-pyridine 

Relevant articles and documents

Discovery and optimization of a novel series of pyrazolyltetrahydropyran N-type calcium channel (Cav 2.2) blockers for the treatment of pain

A novel series of pyrazolyltetrahydropyran N-type calcium channel blockers are described. Structural modifications of the series led to potent compounds in both a cell-based fluorescent calcium influx assay and a patch clamp electrophysiology assay. Representative compounds from the series were bioavailable and showed efficacy in the rat CFA and CCI models of inflammatory and neuropathic pain.