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1-Propanone, 1-(3,4-dimethoxyphenyl)-3-(dimethylamino)-, also known as 3-dimethylaminopropanone (DMAP), is an organic compound with the chemical formula C11H17NO3. It is a colorless to pale yellow liquid that is soluble in water and various organic solvents. DMAP is widely used as a catalyst in organic synthesis, particularly in the formation of amides, esters, and other carbonyl compounds. It functions as a nucleophilic catalyst, enhancing the reactivity of carbonyl groups by forming an intermediate iminium ion. The presence of the dimethoxyphenyl group and the dimethylamino group in its structure contributes to its high catalytic activity and selectivity. Due to its versatility and effectiveness, DMAP is a valuable tool in the field of organic chemistry, particularly in the synthesis of pharmaceuticals, agrochemicals, and other specialty chemicals.

1568-01-0

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1568-01-0 Usage

Structure

Structurally similar to the drug ketamine

Psychoactive substance

Known for its hallucinogenic and dissociative effects when ingested

Mechanism of action

Binds to the NMDA receptor in the brain, leading to altered perception and consciousness

Legal status

Considered a controlled substance in many countries due to its potential for abuse and addiction

Therapeutic potential

Research has shown potential for treating conditions such as depression, anxiety, and PTSD

Availability

Use is highly regulated and illegal in many places

Check Digit Verification of cas no

The CAS Registry Mumber 1568-01-0 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,5,6 and 8 respectively; the second part has 2 digits, 0 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 1568-01:
(6*1)+(5*5)+(4*6)+(3*8)+(2*0)+(1*1)=80
80 % 10 = 0
So 1568-01-0 is a valid CAS Registry Number.

1568-01-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 14, 2017

Revision Date: Aug 14, 2017

1.Identification

1.1 GHS Product identifier

Product name 3-(N,N-dimethylamino)-1-(3,4-dimethoxyphenyl)propan-1-one

1.2 Other means of identification

Product number -
Other names 1-(3,4-dimethoxyphenyl)-3-(dimethylamino)propan-1-one

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:1568-01-0 SDS

1568-01-0Relevant academic research and scientific papers

ARALKYL DIAMINE DERIVATIVES AND USES THEREOF AS ANTIDEPRESSANT

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Paragraph 0029; 0150, (2013/03/28)

Aralkyl diamine derivative of the following formula, pharmaceutically acceptable salts or uses thereof as antidepressants. The derivatives have triplex inhibiting activities of the reuptake of 5-HT, dopamine and noradrenalin, which can be administered to the patients in need of such treatment in the form of compositions orally or injectedly et al.

DIHYDROPYRAZOLES

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Page/Page column 139, (2013/03/26)

Novel dihydropyrazole derivatives of formula (I) wherein L, R, R3, R4, R5, R6, R7, X1, X2, X3, X4, Y, m and n have the meaning according to the claims, are

Synthesis and pharmacological evaluation of 3-aryl-3-azolylpropan-1-amines as selective triple serotonin/norepinephrine/dopamine reuptake inhibitors

Lee, Ki-Ho,Park, Chun-Eung,Min, Kyung-Hyun,Shin, Yong-Je,Chung, Coo-Min,Kim, Hui-Ho,Yoon, Hae-Jeoung,Won-Kim,Ryu, Eun-Ju,Shin, Yu-Jin,Nam, Hyun-Sik,Cho, Jeong-Woo,Lee, Hee-Yoon

scheme or table, p. 5567 - 5571 (2010/12/29)

A series of 3-aryl-3-azolylpropan-1-amines was prepared and screened for its capability of inhibiting monoamine reuptake. Analogs with nanomolar potency, good human in vitro microsomal stability, and low drug-drug interaction potential were described. In

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