1835-04-7

Basic information

• Product Name: 1-(3,4-DIMETHOXY-PHENYL)-PROPAN-1-ONE
• Synonyms: 3',4'-DIMETHOXY-1-PHENYLPROPIOPHENONE;3,4-DIMETHOXYPROPIOPHENONE;1-(3,4-DIMETHOXY-PHENYL)-PROPAN-1-ONE;Ethyl 3,4-dimethoxyphenyl ketone;NSC 16954;Propioveratrone
• CAS NO: 1835-04-7
• Molecular Formula: C₁₁H₁₄O₃
• Molecular Weight: 194.23
• Product Categories: Aromatic Propiophenones (substituted);Aromatics
• Mol File: 1835-04-7.mol
• Article Data: 39

Chemical Properties

• Melting Point: 62–63°C
• Boiling Point: 270.67°C (rough estimate)
• Flash Point: 123.2 ºC
• Appearance: /
• Density: 1.1224 (rough estimate)
• Vapor Pressure: 0.00154mmHg at 25°C
• Refractive Index: 1.4600 (estimate)
• Storage Temp.: Sealed in dry,Room Temperature
• Solubility: Chloroform, Dichloromethane, Ether, Ethyl Acetate, Methanol
• CAS DataBase Reference: 1-(3,4-DIMETHOXY-PHENYL)-PROPAN-1-ONE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(3,4-DIMETHOXY-PHENYL)-PROPAN-1-ONE(1835-04-7)
• EPA Substance Registry System: 1-(3,4-DIMETHOXY-PHENYL)-PROPAN-1-ONE(1835-04-7)

Safety Data

• Statements: 36
• Safety Statements: 26
• Hazardous Substances Data: 1835-04-7(Hazardous Substances Data)

Usage

Chemical Properties

Off-White Semi-Solid

Uses

3,4-Dimethoxypropiophenone (cas# 1835-04-7) is a compound useful in organic synthesis.

Preparation

Preparation by reaction of dimethyl sulfate with propionylcatechol in alkaline solution (43%).

InChI:InChI=1/C11H14O3/c1-4-9(12)8-5-6-10(13-2)11(7-8)14-3/h5-7H,4H2,1-3H3

Upstream product

• 91-16-7 1,2-dimethoxybenzene 
• 802294-64-0 propionic acid 
• 123-62-6 propionic acid anhydride 
• 506-96-7 Acetyl bromide 
• 10548-77-3 1-(3,4-dimethoxyphenyl)-3-hydroxy-2-(2-methoxyphenoxy)propan-1-one 
• 2024-83-1 veratronitrile 
• 57929-25-6 3,4-(diacetyloxy)benzoyl chloride 
• 28281-49-4 3,4-methylenedioxypropiophenone 
• 925-90-6 ethylmagnesium bromide 
• 120-14-9 3,4-dimethoxy-benzaldehyde 
• 811-49-4 ethyllithium 
• 93-07-2 Veratric acid 
• 7451-98-1 3',4'-dihydroxypropiophenone 
• 77-78-1 dimethyl sulfate 

Downstream Products

• 4302-34-5 β-Chlor-α-methyl-3,4-dimethoxy-zimtaldehyd 
• 4440-92-0 1,4-bis(3,4-dimethoxyphenyl),2,3-dimethylbutane-1,4-dione 
• 120-80-9 benzene-1,2-diol 
• 67-56-1 methanol 
• 802294-64-0 propionic acid 
• 1835-05-8 2-bromo-1-(3,4-dimethoxyphenyl)propan-1-one 
• 29515-34-2 1-(4,5-dimethoxy-2-nitro-phenyl)-propan-1-ol 
• 1604832-26-9 (E)-N-(1-(3,4-dimethoxyphenyl)propylidene)-2,2-diethoxyethanamine 
• 93-07-2 Veratric acid 
• 138505-14-3 2-(3,4-dimethoxyphenyl)propanoic acid 
• 24150-24-1 terameprocol 
• 528-63-2 all-cis-3,4-dimethyl-2,5-bis(3,4-dimethoxyphenyl)tetrahydrofuran 

Relevant articles and documents

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Preparation method and application of apocynin and derivatives of apocynin

The invention belongs to the technical field of chemical biology, and particularly relates to a preparation method of apocynin and derivatives of the apocynin and an application of the apocynin and the derivatives of the apocynin in skin care products. The apocynin and the derivatives of the apocynin provided by the invention can promote collagen synthesis, help skin damage repair, and can be usedin the skin care products.

Rhodium-terpyridine catalyzed redox-neutral depolymerization of lignin in water

Simple rhodium terpyridine complexes were found to be suitable catalysts for the redox neutral cleavage of lignin in water. Apart from cleaving lignin model compounds into ketones and phenols, the catalytic system could also be applied to depolymerize dioxasolv lignin and lignocellulose, affording aromatic ketones as the major monomer products. The (hemi)cellulose components in the lignocellulose sample remain almost intact during lignin depolymerization, providing an example of a "lignin-first" process under mild conditions. Mechanistic studies suggest that the reaction proceeds via a rhodium catalyzed hydrogen autotransfer process.

Mild Redox-Neutral Depolymerization of Lignin with a Binuclear Rh Complex in Water

A mild redox-neutral lignin depolymerization system featuring a water-soluble binuclear Rh complex has been developed. The catalytic system could be successfully applied to the depolymerization of a lignin-like polymer, alkaline lignin, as well as raw lignocellulose samples to produce aromatic ketones, providing a homogeneous catalytic system for "lignin-first" biorefinery in water. Mechanistic studies on the model substrate suggest that the reaction proceeds via a metal-catalyzed dehydrogenation step to afford a carbonyl intermediate, followed by C-O bond cleavage to afford ketone and phenol products. Deuterium labeling study shows that the hydrogen used for cleavage of the C-O bond originates from the alcohol moiety in the substrate.