1569272-03-2

Upstream product

• 24588-72-5 2-(4-methoxyphenyl)-1,3-dithiane 
• 459-57-4 4-fluorobenzaldehyde 
• 123-11-5 4-methoxy-benzaldehyde 

Downstream Products

• 1569272-25-8 (S)-(4-fluorophenyl)(2-(4-methoxyphenyl)-1,3-dithian-2-yl)methanol 
• 1569271-93-7 (S)-2-(4-fluorophenyl)-2-hydroxy-1-(4-methoxyphenyl)ethanone 
• 1569271-73-3 (S)-ethyl 2-(4-fluorophenyl)-2-(4-methoxyphenyl)acetate 
• 1569271-78-8 (R)-ethyl 2-(4-fluorophenyl)-2-(4-methoxyphenyl)acetate 
• 1569271-83-5 2-(4-fluorophenyl)-2-hydroxy-1-(4-methoxyphenyl)ethan-1-one 
• 1569271-61-9 ethyl 2-(4-fluorophenyl)-2-(4-methoxyphenyl)acetate 
• 1569272-15-6 (4-fluorophenyl)(2-(4-methoxyphenyl)-1,3-dithian-2-yl)methanone 
• 1569272-21-4 (R)-(4-fluorophenyl)(2-(4-methoxyphenyl)-1,3-dithian-2-yl)methanol 
• 1569271-90-4 (R)-2-(4-fluorophenyl)-2-hydroxy-1-(4-methoxyphenyl)ethanone 

Relevant academic research and scientific papers

Preparation and Application of α-Imino Ketones through One-Pot Tandem Reactions Based on Heyns Rearrangement

α-Imino ketone is a useful building block for the preparation of α-amino ketones and α-amino alcohols. However, its preparation has been seldomly seen. Herein, a metal-free and operationally simple strategy has been developed to generate α-imino ketones with high regioselectivity. Meanwhile, the method allowed for the preparation of various N,O-ketals with high regioselectivities and diastereoselectivities through cascade reactions in one pot.

Synthesis of chiral α-diarylacetic esters by stereospecific 1,2-aryl migration promoted by in situ generated acetals from benzoins

A simple protocol for the synthesis of α-diarylacetic esters from benzoins is described. In situ generated acetal assists rapid 1,2-aryl migration in a stereospecific manner, paving the way to make enantioenriched α-diarylacetic esters from easily accessi