24588-72-5

Basic information

• Product Name: 4-Methoxybenzaldehyde trimethylenedithioacetal
• Synonyms: 2-(4-Methoxyphenyl)-1,3-dithiane;4-Methoxybenzaldehyde trimethylenedithioacetal
• CAS NO: 24588-72-5
• Molecular Formula: C₁₁H₁₄OS₂
• Molecular Weight: 226.3583
• Mol File: 24588-72-5.mol
• Article Data: 89

Chemical Properties

• Melting Point: 121 °C
• Boiling Point: 366.6°Cat760mmHg
• Flash Point: 175.5°C
• Appearance: /
• Density: 1.169g/cm³
• Vapor Pressure: 3.05E-05mmHg at 25°C
• Refractive Index: 1.596
• Solubility: soluble in Acetone
• CAS DataBase Reference: 4-Methoxybenzaldehyde trimethylenedithioacetal(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Methoxybenzaldehyde trimethylenedithioacetal(24588-72-5)
• EPA Substance Registry System: 4-Methoxybenzaldehyde trimethylenedithioacetal(24588-72-5)

Safety Data

• Hazardous Substances Data: 24588-72-5(Hazardous Substances Data)

Usage

General Description

4-Methoxybenzaldehyde trimethylenedithioacetal is a chemical compound with the molecular formula C12H14O2S2. It is a liquid at room temperature and is commonly used as an organic synthesis intermediate. 4-Methoxybenzaldehyde trimethylenedithioacetal is often used in the production of pharmaceuticals, fragrances, and other fine chemicals. It has a strong odor and can be irritating to the skin and respiratory system. The chemical properties of 4-Methoxybenzaldehyde trimethylenedithioacetal make it useful in a wide range of industrial applications, and it is an important building block in the production of various synthetic compounds.

InChI:InChI=1/C11H14OS2/c1-12-10-5-3-9(4-6-10)11-13-7-2-8-14-11/h3-6,11H,2,7-8H2,1H3

Upstream product

• 109-80-8 1.3-propanedithiol 
• 123-11-5 4-methoxy-benzaldehyde 
• 544-25-2 Cyclohepta-1,3,5-triene 
• 2186-92-7 p-Anisaldehyde dimethyl acetal 
• 14202-31-4 4-methoxybenzaldehyde-1,1-diacetate 
• 55727-23-6 3‐(1,3-dithiane-2-yl)pentane-2,4-dione 
• 57529-04-1 2-chloro-1,3-dithiane 
• 505-23-7 1,3 dithiane 
• 69278-13-3 2-(4-methoxyphenyl)-1,3-dithiane 1-oxide 
• 23837-15-2 1-(bis(ethylthio)methyl)-4-methoxybenzene 
• 6712-20-5 2-(4-methoxyphenyl)-[1,3]dithiolane 
• 6784-58-3 1-(1,3-dithian-2-ylidene)propan-2-one 
• 2403-50-1 2-(4-methoxyphenyl)-1,3-dioxolane 
• 682360-46-9 2-(1,3-dithian-2-ylidene)-3-oxobutanoic acid 

Downstream Products

• 129959-16-6 8-Methoxy-1-<2-(4'-methoxyphenyl)-1,3-dithiane-2-yl>-isoquinoline 
• 123-11-5 4-methoxy-benzaldehyde 
• 79032-16-9 1,2-dithiolane 1-oxide 
• 111997-78-5 2-(4-Methoxyphenyl)-1,3-dithian-2-ylium-tribromid 
• 156387-49-4 Bis<3-(4-methoxybenzoylsulfanyl)propyl> disulfide 
• 128155-61-3 2-(4-Methoxyphenyl)-2-thiomethoxy-1,3-dithiane 
• 215813-56-2 2,2'-Bis-(4-methoxy-phenyl)-[2,2']bi[[1,3]dithianyl] 
• 5689-71-4 2-(4-methoxy-phenyl)-[1,3]dioxane 
• 591-31-1 3-methoxy-benzaldehyde 
• 121-98-2 methyl 4-methoxybenzoate 
• 100-09-4 4-methoxybenzoic acid 
• 461051-85-4 2-(4-methoxyphenyl)-2-triethylsilyl-1,3-dithiane 
• 932033-73-3 2-(4-methoxy-phenyl)-2-(3,4,5-trimethoxy-benzyl)-[1,3]dithiane 
• 881883-56-3 (S)-4-(4-methoxyphenyl)-3,N,N-trimethyl-4-oxo-butyramide 

Relevant articles and documents

PhIO-Mediated oxidative dethioacetalization/dethioketalization under water-free conditions

Treatment of thioacetals and thioketals with iodosobenzene in anhydrous DCM conveniently afforded the corresponding carbonyl compounds in high yields under water-free conditions. The mechanistic studies indicate that this dethioacetalization/dethioketalization process does not need water and the oxygen of the carbonyl products comes from the hypervalent iodine reagent.

Highly ordered mesoporous functionalized pyridinium protic ionic liquid framework as a highly efficient catalytic system in chemoselective thioacetalization of carbonyl compounds under solvent-free conditions

Dithioacetals are a well-known class of organic compounds as both protecting group for the carbonyl compounds and valuable synthons for organic synthesis. Polysiloxane acidic ionic liquids containing pyridinium trifluoroacetate salts (PMO-Py-IL) as organi

Dehydrative Glycosylation Enabled by a Comproportionation Reaction of 2-Aryl-1,3-dithiane 1-Oxide?

A new dehydrative glycosylation reaction has been established by capitalizing on the comproportionation reaction of 2-aryl-1,3-dithiane 1-oxides promoted by triflic anhydride (Tf2O). By wedding the high potency of thiophilic promoter system with the step efficiency of dehydrative glycosylation, this reagent underwent facile intermolecular oxothio acetalization with C1-hemiacetal donor to install a temporary leaving group, rendering a transient electrophilic center at the remote site to the anomeric position. The sulfenyl triflate tethered at the terminus concomitantly activated the sulfide intramolecularly to afford the oxocarbenium ion, thereby facilitating the title glycosylation. Aside from accommodating broad range functional groups and inactive hemiacetal substrates, the present activation protocol also proved expedient for 1,3-diol protection. Most importantly, this method further provided a fresh perspective for the application of sulfur chemistry to carbohydrate chemistry.