1570-76-9

Basic information

• Product Name: 4-CHLORO-2,3-DIMETHYLPHENOL
• Synonyms: 4-CHLORO-2,3-DIMETHYLPHENOL;2,3-Xylenol, 4-chloro- (8ci);4-Chloro-2,3-xylenol;Nsc 60150;Phenol, 4-chloro-2,3-dimethyl-;Phenol, 4-chloro-2,3-dimethyl- (9ci)
• CAS NO: 1570-76-9
• Molecular Formula: C₈H₉ClO
• Molecular Weight: 156.61
• Mol File: 1570-76-9.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 4-CHLORO-2,3-DIMETHYLPHENOL(CAS DataBase Reference)
• NIST Chemistry Reference: 4-CHLORO-2,3-DIMETHYLPHENOL(1570-76-9)
• EPA Substance Registry System: 4-CHLORO-2,3-DIMETHYLPHENOL(1570-76-9)

Safety Data

• Hazardous Substances Data: 1570-76-9(Hazardous Substances Data)

Usage

InChI:InChI=1/C8H9ClO/c1-5-6(2)8(10)4-3-7(5)9/h3-4,10H,1-2H3

Upstream product

• 526-75-0 2,3-Dimethylphenol 
• 7791-25-5 sulfuryl dichloride 
• 64-19-7 acetic acid 

Downstream Products

• 14804-26-3 4-chloro-2,3-dimethylanisole 
• 211363-27-8 4-Chloro-2,3-dimethyl-6-nitrophenol 
• 1420231-01-1 (R)-4-chloro-6-fluoro-5,6-dimethylcyclohexa-2,4-dienone 
• 60962-83-6 1-[3,5-Dichloro-4-(4-chloro-2,3-dimethyl-phenoxy)-phenyl]-3-((E)-3-ethoxy-acryloyl)-urea 
• 60963-38-4 3,5-Dichloro-4-(4-chloro-2,3-dimethyl-phenoxy)-phenylamine 
• 75552-10-2 6-Aminomethyl-4-chloro-2,3-dimethyl-phenol; hydrochloride 
• 182010-82-8 (E)-6-(5-Chloro-2-methoxy-3,4-dimethyl-phenyl)-4-methyl-hex-4-enoic acid methyl ester 
• 182010-81-7 methyl (E)-6-(5-chloro-2-hydroxy-3,4-dimethylphenyl)-4-methyl-4-hexenoic acid 
• 60963-10-2 C₁₄H₁₀Cl₃NO₃ 

Relevant articles and documents

SUBSTITUTED CARBAZOLE COMPOUNDS

Disclosed are compounds of Formula (I) or salts thereof, wherein R1, R2, R3, R4, and R5 are defined herein. Also disclosed are methods of using such compounds as inhibitors of signaling through Toll-l

Benzoxazole derivatives as novel 5-HT3 receptor partial agonists in the gut

A series of benzoxazoles with a nitrogen-containing heterocyclic substituent at the 2-position was prepared and evaluated for 5-HT3 partial agonist activity on isolated guinea pig ileum. The nature of the substituent at the 5-position of the benzoxazole ring affected the potency for the 5-HTs receptor, and the 5-chloro derivatives showed increased potency and lowered intrinsic activity. 5-Chloro-7-methyl-2-(4-methyl-1- homopiperazinyl)benzoxazole (6v) exhibited a high binding affinity in the same range as that of the 5-HT3 antagonist granisetron, and its intrinsic activity was 12% of that of 5-HT. Compound 6v inhibited 5-HT-evoked diarrhea but did not prolong the transition time of glass beads in the normal distal colon even at a dose of 100 times the ED50 for diarrhea inhibition in mice. Compounds of this type are expected to be effective for the treatment of irritable bowel syndrome without the side effect of constipation.