157255-72-6

Basic information

• Product Name: 2-METHYL-4-IODO-1-TRITYLIMIDAZOLE
• Synonyms: 2-METHYL-4-IODO-1-TRITYLIMIDAZOLE;2-METHYL-4-IODO-1-TRITYLIMIDAZOLE,98%;4-iodo-2-Methyl-1-trityl-1H-iMidazole;1H-IMidazole, 4-iodo-2-Methyl-1-(triphenylMethyl)-;4-Iodo-2-methyl-1-(triphenylmethyl)-1H-imidazole
• CAS NO: 157255-72-6
• Molecular Formula: C₂₃H₁₉IN₂
• Molecular Weight: 450.31
• Product Categories: Imidazol&Benzimidazole
• Mol File: 157255-72-6.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 491.367 °C at 760 mmHg
• Flash Point: 250.97 °C
• Appearance: /
• Density: 1.38 g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.646
• PKA: 4.53±0.60(Predicted)
• CAS DataBase Reference: 2-METHYL-4-IODO-1-TRITYLIMIDAZOLE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-METHYL-4-IODO-1-TRITYLIMIDAZOLE(157255-72-6)
• EPA Substance Registry System: 2-METHYL-4-IODO-1-TRITYLIMIDAZOLE(157255-72-6)

Safety Data

• Hazardous Substances Data: 157255-72-6(Hazardous Substances Data)

Usage

General Description

2-Methyl-4-iodo-1-tritylimidazole is a chemical compound that belongs to the class of imidazoles. It is a white to off-white solid substance with a molecular formula of C21H17IN2 and a molecular weight of 422.28 g/mol. The compound is commonly used as a building block in the synthesis of various pharmaceutical compounds and organic materials. Its unique structure and properties make it suitable for use in the development of new and innovative products. The compound can be produced through various synthetic methods and is available for purchase from chemical suppliers.

InChI:InChI=1/C23H19IN2/c1-18-25-22(24)17-26(18)23(19-11-5-2-6-12-19,20-13-7-3-8-14-20)21-15-9-4-10-16-21/h2-17H,1H3

Upstream product

• 73746-45-9 4-iodo-2-methyl-1H-imidazole 
• 76-83-5 trityl chloride 
• 73746-45-9 4⁽⁵⁾-iodo-2-methyl-1H-imidazole 

Downstream Products

• 1022155-26-5 C₃₉H₃₂F₆N₄O 
• 1021736-30-0 2-methyl-4-{[1-(trifluoromethyl)cyclopropyl]methyl}-1-trityl-1H-imidazole 
• 1022154-58-0 (2-methyl-1-trityl-1H-imidazol-4-yl)-(1-trifluoromethyl-cyclopropyl)-methanone 

Relevant articles and documents

Important Hydrogen Bond Networks in Indoleamine 2,3-Dioxygenase 1 (IDO1) Inhibitor Design Revealed by Crystal Structures of Imidazoleisoindole Derivatives with IDO1

Indoleamine 2,3-dioxygenase 1 (IDO1), promoting immune escape of tumors, is a therapeutic target for the cancer immunotherapy. A number of IDO1 inhibitors have been identified, but only limited structural biology studies of IDO1 inhibitors are available t

Direct synthesis of pyrroles via a silver-promoted three-component reaction involving unusual imidazole ring opening

A novel silver-promoted three-component reaction toward the synthesis of multifunctionalized pyrroles has been developed. This reaction involves an unusual imidazole ring decomposition, presumably via 1,5-isomerization and subsequent hydrolysis.

Substituted inmidazoles as bombesin receptor subtype-3 modulators

Certain novel substituted imidazoles are ligands of the human bombesin receptor and, in particular, are selective ligands of the human bombesin receptor subtype-3 (BRS-3). They are therefore useful for the treatment, control, or prevention of diseases and disorders responsive to the modulation of BRS-3, such as obesity, and diabetes.