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(2-methyl-1-trityl-1H-imidazol-4-yl)-(1-trifluoromethyl-cyclopropyl)-methanone is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

1022154-58-0

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1022154-58-0 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1022154-58-0 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,2,2,1,5 and 4 respectively; the second part has 2 digits, 5 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 1022154-58:
(9*1)+(8*0)+(7*2)+(6*2)+(5*1)+(4*5)+(3*4)+(2*5)+(1*8)=90
90 % 10 = 0
So 1022154-58-0 is a valid CAS Registry Number.

1022154-58-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 13, 2017

Revision Date: Aug 13, 2017

1.Identification

1.1 GHS Product identifier

Product name (2-methyl-1-tritylimidazol-4-yl)-[1-(trifluoromethyl)cyclopropyl]methanone

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:1022154-58-0 SDS

1022154-58-0Relevant academic research and scientific papers

Discovery of MK-5046, a potent, selective bombesin receptor subtype-3 agonist for the treatment of obesity

Sebhat, Iyassu K.,Franklin, Christopher,Lo, Michael M.-C.,Chen, David,Jewell, James P.,Miller, Randy,Pang, Jianmei,Palyha, Oksana,Kan, Yanqing,Kelly, Theresa M.,Guan, Xiao-Ming,Marsh, Donald J.,Kosinski, Jennifer A.,Metzger, Joseph M.,Lyons, Kathryn,Dragovic, Jasminka,Guzzo, Peter R.,Henderson, Alan J.,Reitman, Marc L.,Nargund, Ravi P.,Wyvratt, Matthew J.,Lin, Linus S.

, p. 43 - 47 (2011/04/17)

We report the development and characterization of compound 22 (MK-5046), a potent, selective small molecule agonist of BRS-3 (bombesin receptor subtype-3). In pharmacological testing using diet-induced obese mice, compound 22 caused mechanism-based, dose-

Substituted inmidazoles as bombesin receptor subtype-3 modulators

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Page/Page column 28, (2010/02/17)

Certain novel substituted imidazoles are ligands of the human bombesin receptor and, in particular, are selective ligands of the human bombesin receptor subtype-3 (BRS-3). They are therefore useful for the treatment, control, or prevention of diseases and disorders responsive to the modulation of BRS-3, such as obesity, and diabetes.

A practical, kilogram-scale implementation of the Wolff-Kishner reduction

Kuethe, Jeffrey T.,Childers, Karla G.,Peng, Zhihui,Journet, Michel,Humphrey, Guy R.,Vickery, Thomas,Bachert, Donald,Lam, Thientu T.

experimental part, p. 576 - 580 (2010/04/22)

A safe and practical strategy has been developed for the largescale preparation of imidazole 7. The key transformation involved the Wolff-Kishner reduction of the sterically demanding neopentyl- trifluoromethylcyclopropyl imidazole ketone 8. The described

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