15733-07-0Relevant academic research and scientific papers
The reaction of grignard reagents with bunte salts: A thiol-free synthesis of sulfides
Reeves, Jonathan T.,Camara, Kaddy,Han, Zhengxu S.,Xu, Yibo,Lee, Heewon,Busacca, Carl A.,Senanayake, Chris H.
supporting information, p. 1196 - 1199 (2014/03/21)
S-Alkyl, S-aryl, and S-vinyl thiosulfate sodium salts (Bunte salts) react with Grignard reagents to give sulfides in good yields. The S-alkyl Bunte salts are prepared from odorless sodium thiosulfate by an SN2 reaction with alkyl halides. A Cu-
BIOTRANSFORMATION OF ORGANIC SULFIDES. PART 6. FORMATION OF CHIRAL para-SUBSTITUTED BENZYL METHYL SULFOXIDES BY HELMINTHOSPORIUM SPECIES NRRL 4671
Holland, Herbert L.,Brown, Frances M.,Larsen, Brett G.
, p. 1561 - 1568 (2007/10/02)
The fungus Helminthosporium species NRRL 4671 has been used for the biotransformation of a series of para-substituted benzyl sulfides with substituent groups consisting of trifluoromethyl, halo, hydroxy, methoxy, acetoxy, nitro, cyano, amino, acetamido, acyl and carboxylic acid units.In all cases, sulfoxide formation occurred in good yoeld and with predominant (S) chirality at the sulfur position.A minor amount of sulfone product was also obtained from the halo- and methoxy-substituted substrates.
Superelectrophilic methylthiomethylation of aromatics with chloromethyl methyl sulfide/aluminum chloride (MeSCH2Cl:2 AlCl3) reagent
Olah,Wang,Neyer
, p. 276 - 278 (2007/10/02)
Effective methylthiomethylation of aromatics was achieved by using chloromethyl methyl sulfide/aluminum chloride (MeSCH2Cl:2 AlCl3) as the alkylating agent. Excess aluminum chloride activates the thiocarboxonium ion intermediate by coordinating with sulfur and thus diminishes back donation of 'electron density' into the carbocationic center, rendering it a superelectrophilic methylthiomethylating agent.
NOVEL AND EFFECTIVE METHODS FOR α-THIOALKYLATION OF AROMATIC COMPOUNDS
Torisawa, Yasuhiro,Satoh, Atsushi,Ikegami, Shiro
, p. 1729 - 1732 (2007/10/02)
Convenient and effective methods for the introduction of a methylthiomethyl group and other α-thioalkyl group into aromatic compounds are described.
