157394-81-5Relevant academic research and scientific papers
Toward the total synthesis of lophotoxin - New methodologies and synthetic strategies
Wipf, Peter,Grenon, Michel
, p. 1226 - 1241 (2007/10/03)
Our recent progress toward the synthesis of the furanocembranolide lophotoxin (1) is disclosed. Strategies for the stereoselective incorporation of the C13 stereocenter by a catalytic desymmetrization of a cyclic meso-anhydride, as well as a no
Total Synthesis of the Ethanol Inducible, Proinflammatory Autacoid 3(S)-Hydroxy-Leukotriene B4 (3-OH-LTB4) and Analogues
Chauhan, Kamlesh,Bhatt, Rama K.,Falck, J. R.,Capdevila, Jorge H.
, p. 1825 - 1828 (2007/10/02)
3(S)-Hydroxy-Leukotriene B4 (1a), its 3(R)-epimer 1b, and 14,15-acetylenic analogue were efficiently prepared via chelation-controlled reduction of ketone 12, obtained by acetylide addition to chiral β-hydroxylactones 7/9. - Key Words: eicosanoid, chelati
