157394-79-1Relevant articles and documents
Total Synthesis of the Ethanol Inducible, Proinflammatory Autacoid 3(S)-Hydroxy-Leukotriene B4 (3-OH-LTB4) and Analogues
Chauhan, Kamlesh,Bhatt, Rama K.,Falck, J. R.,Capdevila, Jorge H.
, p. 1825 - 1828 (2007/10/02)
3(S)-Hydroxy-Leukotriene B4 (1a), its 3(R)-epimer 1b, and 14,15-acetylenic analogue were efficiently prepared via chelation-controlled reduction of ketone 12, obtained by acetylide addition to chiral β-hydroxylactones 7/9. - Key Words: eicosanoid, chelati