157487-15-5Relevant academic research and scientific papers
Analysis of hydroxylamine glycosidic linkages: Structural consequences of the NO bond in calicheamicin
Walker, Suzanne,Gange, David,Gupta, Varsha,Kahne, Daniel
, p. 3197 - 3206 (1994)
The antitumor activity of calicheamicin is related to its ability to bind to and cleave double-stranded DNA. There is substantial evidence that the oligosaccharide-aryl tail of calicheamicin plays a critical role in the binding selectivity. The calicheami
