Journal of the American Chemical Society p. 3197 - 3206 (1994)
Update date:2022-08-05
Topics:
Walker, Suzanne
Gange, David
Gupta, Varsha
Kahne, Daniel
The antitumor activity of calicheamicin is related to its ability to bind to and cleave double-stranded DNA. There is substantial evidence that the oligosaccharide-aryl tail of calicheamicin plays a critical role in the binding selectivity. The calicheami
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