157487-30-4

Upstream product

• 33719-74-3 3,5-dichloroanisole 
• 75-36-5 acetyl chloride 
• 82772-93-8 2,6-dichloro-4-methoxy-benzaldehyde 
• 100-06-1 1-(4-methoxyphenyl)ethanone 
• 157487-23-5 1-(2,6-dichloro-4-methoxyphenyl)ethan-1-ol 

Downstream Products

• 157487-25-7 trans-1,3-bis-(2,6-dichloro-4-methoxyphenyl)-2-propen-1-one 
• 1439936-11-4 N-(4-(2,6-dichloro-4-methoxyphenyl)thiazol-2-yl)isonicotinamide 
• 1439936-13-6 4-(2,6-dichloro-4-methoxyphenyl)thiazol-2-ylamine 
• 1439936-12-5 2-bromo-1-(2,6-dichloro-4-methoxyphenyl)ethanone 
• 157487-29-1 1,3-bis-(2,6-dichloro-4-methoxyphenyl)-2,3-dibromopropan-1-one 

Relevant academic research and scientific papers

IMPROVED MODULATORS OF HEC1 ACTIVITY AND METHODS THEREFOR

Compounds, compositions, and methods for modulation of Hec1/Nek2 interaction are provided. Such compounds disrupt Nek2/Hec1 binding and may be useful as chemotherapeutic agents for neoplastic diseases

A simple, efficient and regioselective oxychlorination of aromatic compounds using ammonium chloride and oxone

A simple, efficient, mild and regioselective method for oxychlorination of aromatic compounds is reported. The electrophilic substitution of chlorine generated in situ from NH4Cl as a chlorine source and oxone as an oxidant is reported for the first time.

Formation of 1H-aziridines from chalcones and hydroxylamine

Highly substituted chalcones 1 do not react with two molecules of hydroxylamine affording dioximes 2 or hydroxyamino-oximes 3 as expected according to von Auwers' procedure: only one molecule of hydroxylamine is consumed leading to trans-configurated 2-be