15763-01-6

Basic information

• Product Name: L-(+)-TARTARIC ACID DI-N-BUTYL ESTER
• Synonyms: (+)-Di-n-butyl-L-tartrat;(2R,3R)-2,3-dihydroxysuccinic acid dibutyl ester;dibutyl (2R,3R)-2,3-dihydroxybutanedioate
• CAS NO: 15763-01-6
• Molecular Formula: C12H20O6-2
• Molecular Weight: 260.2836
• Product Categories: Chiral Building Blocks;Esters (Chiral);Synthetic Organic Chemistry
• Mol File: 15763-01-6.mol
• Article Data: 13

Chemical Properties

• Flash Point: 160 °C
• Appearance: /
• Density: 1.09
• Refractive Index: 10.5 ° (C=neat)
• CAS DataBase Reference: L-(+)-TARTARIC ACID DI-N-BUTYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: L-(+)-TARTARIC ACID DI-N-BUTYL ESTER(15763-01-6)
• EPA Substance Registry System: L-(+)-TARTARIC ACID DI-N-BUTYL ESTER(15763-01-6)

Safety Data

• Hazardous Substances Data: 15763-01-6(Hazardous Substances Data)

Usage

Uses

Dibutyl L-Tartrate is an inhibitor of human prostatic acid phosphatase, a uniquely expressed enzyme found in prostatic tissue and prostate cancer.

Upstream product

• 87-69-4 tartaric acid 
• 71-36-3 butan-1-ol 
• 133-37-9 DL-tartaric acid 
• 87-69-4 L-Tartaric acid 
• 147-71-7 D-tartaric acid 
• 298-12-4 Glyoxilic acid 
• 109-65-9 1-bromo-butane 
• 622-00-4 dibenzyl (2R,3R)-2,3-dihydroxybutanedioate 

Downstream Products

• 2319-57-5 threitol 
• 82807-35-0 2-butenedioic acid dibutyl ester 
• 74479-40-6 butyl {(2E,4E,6E,8E)-9-(4-methoxy-2,3,6-trimethyl)phenyl-3,7-dimethylnona-2,4,6.8}tetraenoate 
• 1610451-59-6 dibutyl-2,3-bis(dibenzylphospho)-L-tartrate 

Relevant articles and documents

Synthesis and application of 2,3-Dihydroxybutanedioic Acid Esters as efficient additives in Methanol-Gasoline

In this paper, 2,3-dihydroxybutanedioic acid esters (tartaric esters) were synthesized and used as phase stabilizer and saturation vapour pressure depressor of methanol-gasoline. The results show that the stabilities of the methanol-gasoline depend on the

Superoxide dismutase mimetics. Part 2: Synthesis and structure-activity relationship of glyoxylate- and glyoxamide-derived metalloporphyrins

Novel glyoxylate- and glyoxamide-derived metalloporphyrins 26-58 were synthesized and evaluated as potential superoxide dismutase (SOD) mimetics. Relative to previously studied MnTBAP analogues, the glyoxylate-derived metalloporphyrins 32, 39, and 54 and glyoxamide-derived metalloporphyrin 49, exhibited enhanced activity in the SOD assay and the majority of the analogues in the current series showed enhanced inhibition of lipid peroxidation and catalase activity.

Enantioselective distribution of amino-alcohols in a liquid-liquid two-phase system containing dialkyl L-tartrate and boric acid

Racemic amino-alcohols such as pindolol, propranolol, alprenolol and bucumolol enantiomers exhibited different distribution behaviors in a two-phase system consisting of a chloroform solution of didodecyl L-tartrate and an aqueous solution of boric acid. It seemed that a borate complex of the 1,2-diol group of the tartrate and the amino-alcohol was formed in the system. In the case of pindolol, one enantiomer was preferentially extracted into the organic phase (x 2.20) at equilibrium.

Synthetic Access to All Four Stereoisomers of Oxetin

A short synthesis of all four stereoisomers of 3-amino-2-oxetanecarboxylic acid (oxetin) is described. The oxetane core is built using a Paternò-Büchi photochemical [2 + 2] cycloaddition; from the key intermediates, complementary resolution protocols provide access to enantiomerically pure oxetin and epi-oxetin on gram-scale.

Reductive coupling of aldehydes by H2S in aqueous solutions, a C-C bond forming reaction of prebiotic interest

We report here a novel reductive coupling reaction of conjugated, non- or poorly enolizable aldehydes induced by H2S and operative in aqueous solutions under prebiotically relevant conditions. This reaction leads from retinal to β-carotene, and from benzylic aldehydes to the corresponding diarylethylenes. This novel reaction also opens a new potentially prebiotic pathway leading from glyoxylic acid to various compounds that are involved in the reductive tricarboxylic acid cycle. This C-C bond forming reaction of prebiotic interest might have been operative, notably, in the sulfide-rich environments of hydrothermal vents, which have been postulated as possible sites for the first steps of organic chemical evolution.