157690-43-2

Basic information

• Product Name: Phosphonic acid, [2-(4-methylphenyl)-2-phenylethenyl]-, diethyl ester, (E)-
• CAS NO: 157690-43-2
• Molecular Formula: C19H23O3P
• Molecular Weight: 330.364
• Mol File: 157690-43-2.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Phosphonic acid, [2-(4-methylphenyl)-2-phenylethenyl]-, diethyl ester, (E)-(CAS DataBase Reference)
• NIST Chemistry Reference: Phosphonic acid, [2-(4-methylphenyl)-2-phenylethenyl]-, diethyl ester, (E)-(157690-43-2)
• EPA Substance Registry System: Phosphonic acid, [2-(4-methylphenyl)-2-phenylethenyl]-, diethyl ester, (E)-(157690-43-2)

Safety Data

• Hazardous Substances Data: 157690-43-2(Hazardous Substances Data)

Upstream product

• 536-74-3 phenylacetylene 
• 3450-67-7 diethyl phenylethynylphosphonate 
• 4294-57-9 para-methylphenylmagnesium bromide 
• 25362-01-0 (Z)-diethyl styrylphosphonate 
• 696-61-7 4-tolylmagnesium chloride 
• 6749-78-6 4-methylphenylmagnesium iodide 

Relevant articles and documents

Enantioselective Synthesis of Chiral Phosphonates via Rh/f-spiroPhos Catalyzed Asymmetric Hydrogenation of β,β-Disubstituted Unsaturated Phosphonates

The first asymmetric hydrogenation of β,β-diaryl unsaturated phosphonates has been realized for synthesis of β,β-diaryl chiral phosphonates with excellent enantioselectivities (up to 99.9% ee) catalyzed by the Rh-(R,R)-f-spiroPhos complex. Furthermore, this catalyst also exhibits comparably excellent performance for β-aryl-β-alkyl unsaturated phosphonates providing the corresponding chiral phosphonates with up to 99.9% ee values. This methodology provides a straightforward access to asymmetric synthesis of chiral phosphonates.

A convenient stereoselective synthesis of disubstituted alk-1-enyl phosphonates

A stereoselective synthesis of disubstituted diethyl alk-1-enylphosphonates has been developed via syn addition of RMgX/CuCl to alk-1-inylphosphonates. Key words: Phosphonate; Stereoselective synthesis; Cuprate addition; Phosphorus