15778-82-2Relevant academic research and scientific papers
A Convenient Synthesis of Corgoine
Masood, M.,Tiwari, K. P.
, p. 825 - 826 (2007/10/02)
2-bromo-4-benzyloxy-5-methoxyphenylacetic acid (1) on condensation with 4-benzyloxybenzylamine (2) furnishes N-(4'-benzyloxybenzyl)-2-bromo-4-benzyloxy-5-methoxyphenylacetamide (3).A stream of CO when passed through amide (3) i n-Bu3N, in the presence of
A NOVEL ROUTE TO THE SYNTHESIS OF SUBSTITUTED N-BENZYL-1,2,3,4-TETRAHYDROISOQUINOLINES. SYNTHESIS OF SENDAVERINE AND CORGOINE
Masood, M.,Tiwari, K. P.
, p. 177 - 182 (2007/10/02)
The condensation product of 2-aminoethanol with substituted benzaldehyde was reduced and N-benzylated with substituted benzyl chloride followed by PPA cyclization to obtain substituted N-benzyl-tetrahydroisoquinolines; likewise the condensation product of
SYNTHESIS OF HETEROCYCLES VIA LACTONES. PART VII. A NEW TOTAL SYNTHESIS OF CORGOINE
Pandey, Ganesh D.,Tiwari, Kamla P.
, p. 763 - 766 (2007/10/02)
A new total synthesis of N-benzyltetrahydroisoquinoline alkaloid, corgoine (7), is described.Treatment of 3-methoxy-4-benzyloxyphenylacetic acid (1) with 37percent formalin and concentrated HCl yielded 6-methoxy-7-benzyloxy-3-isochromanone (2).Compound 2
