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22171-15-9

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22171-15-9 Usage

General Description

4-Benzyloxybenzylamine, also known as N-(4-benzyloxyphenyl)methanamine, is a chemical compound that belongs to the class of organic compounds known as anilines. It is an aromatic amine with a benzyl group attached to the amino group. 4-Benzyloxybenzylamine is commonly used as an intermediate in the synthesis of various pharmaceuticals and organic compounds. It is also used as a building block in the preparation of various advanced materials and chemical products. 4-Benzyloxybenzylamine has a wide range of applications, including its use in the production of drugs, dyes, and other important industrial chemicals. Its chemical structure and properties make it a versatile and valuable compound in various fields of chemistry and industry.

Check Digit Verification of cas no

The CAS Registry Mumber 22171-15-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,2,1,7 and 1 respectively; the second part has 2 digits, 1 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 22171-15:
(7*2)+(6*2)+(5*1)+(4*7)+(3*1)+(2*1)+(1*5)=69
69 % 10 = 9
So 22171-15-9 is a valid CAS Registry Number.

22171-15-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name (4-phenylmethoxyphenyl)methanamine

1.2 Other means of identification

Product number -
Other names 4-Benzyloxybenzylamine

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:22171-15-9 SDS

22171-15-9Relevant articles and documents

Reusable Co-nanoparticles for general and selectiveN-alkylation of amines and ammonia with alcohols

Beller, Matthias,Gawande, Manoj B.,Jagadeesh, Rajenahally V.,Kadam, Ravishankar G.,Li, Xinmin,Ma, Zhuang,Petr, Martin,Zbo?il, Radek,Zhou, Bei

, p. 111 - 117 (2022/01/06)

A general cobalt-catalyzedN-alkylation of amines with alcohols by borrowing hydrogen methodology to prepare different kinds of amines is reported. The optimal catalyst for this transformation is prepared by pyrolysis of a specific templated material, which is generatedin situby mixing cobalt salts, nitrogen ligands and colloidal silica, and subsequent removal of silica. Applying this novel Co-nanoparticle-based material, >100 primary, secondary, and tertiary amines includingN-methylamines and selected drug molecules were conveniently prepared starting from inexpensive and easily accessible alcohols and amines or ammonia.

General and selective synthesis of primary amines using Ni-based homogeneous catalysts

Beller, Matthias,Chandrashekhar, Vishwas G.,Jagadeesh, Rajenahally V.,Jiao, Haijun,Murugesan, Kathiravan,Wei, Zhihong

, p. 4332 - 4339 (2020/05/18)

The development of base metal catalysts for industrially relevant amination and hydrogenation reactions by applying abundant and atom economical reagents continues to be important for the cost-effective and sustainable synthesis of amines which represent highly essential chemicals. In particular, the synthesis of primary amines is of central importance because these compounds serve as key precursors and central intermediates to produce value-added fine and bulk chemicals as well as pharmaceuticals, agrochemicals and materials. Here we report a Ni-triphos complex as the first Ni-based homogeneous catalyst for both reductive amination of carbonyl compounds with ammonia and hydrogenation of nitroarenes to prepare all kinds of primary amines. Remarkably, this Ni-complex enabled the synthesis of functionalized and structurally diverse benzylic, heterocyclic and aliphatic linear and branched primary amines as well as aromatic primary amines starting from inexpensive and easily accessible carbonyl compounds (aldehydes and ketones) and nitroarenes using ammonia and molecular hydrogen. This Ni-catalyzed reductive amination methodology has been applied for the amination of more complex pharmaceuticals and steroid derivatives. Detailed DFT computations have been performed for the Ni-triphos based reductive amination reaction, and they revealed that the overall reaction has an inner-sphere mechanism with H2metathesis as the rate-determining step.

An Inhospitable Cryptand: The Importance of Conformational Freedom in Host-Guest Complexation

Gibson, Harry W.,Huang, Feihe,Zhao, Run,Shao, Li,Zakharov, Lev N.,Slebodnick, Carla,Rheingold, Arnold L.

, p. 3472 - 3479 (2019/03/27)

Two new cryptands were synthesized from bis(5-bromomethyl-1,3-phenylene)-32-crown-10 (4). The third arms, containing 19 or 21 atoms, were installed via Williamson ether syntheses with bisphenols containing 2,6-disubstituted pyridines. 2,6-Diaminopyridine

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