15784-82-4 Usage
Type of compound
Cyanamide derivative
Composition
Adamantyl group and cyano group connected by an amine linker
Usage
Building block in organic synthesis and medicinal chemistry
Potential applications
Precursor for the synthesis of other organic compounds, pharmacological properties, antiviral agent, and ligand in catalytic reactions
Adamantyl group
A saturated hydrocarbon group consisting of a diamondoid structure of carbon atoms
Cyano group
A cyanide group (CN) bonded to a carbon atom
Amine linker
A nitrogen atom bonded to two carbon atoms via single bonds
Organic synthesis
The process of chemically synthesizing organic compounds
Medicinal chemistry
The study of the chemistry and biochemistry of drugs
Pharmacological properties
The actions and effects of a drug on the body
Antiviral agent
A substance that is used to treat viral infections
Catalytic reactions
Reactions that are sped up by the presence of a catalyst or a substance that increases the rate of a reaction without being consumed in the process.
Check Digit Verification of cas no
The CAS Registry Mumber 15784-82-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,5,7,8 and 4 respectively; the second part has 2 digits, 8 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 15784-82:
(7*1)+(6*5)+(5*7)+(4*8)+(3*4)+(2*8)+(1*2)=134
134 % 10 = 4
So 15784-82-4 is a valid CAS Registry Number.
15784-82-4Relevant articles and documents
Comparison of the Pharmacological Activity and Safety of 1-Adamantylguanidine and 3,5-Dimethyl-1-Adamantylguanidine to those of Memantine
Gmiro,Serdyuk
, p. 1198 - 1204 (2021)
Guanidine-containing analogs of amantadine and memantine, including 1-adamantylguanidine hydrochloride (IEM-2151) and 3,5-dimethyl-1-adamantylguanidine hydrochloride (IEM-2163), were synthesized and studied. IEM-2151 and IEM-2163 had greater antihypoxic, anticonvulsant, and neuroprotective activity than memantine; exhibited equally potent antiparkinsonian, antidepressant, and analgesic activity with memantine; and had higher therapeutic indices than memantine.
Selective Gold-Catalysed Synthesis of Cyanamides and 1-Substituted 1H-Tetrazol-5-Amines from Isocyanides
?koch, Karel,Císa?ová, Ivana,?těpni?ka, Petr
supporting information, p. 13788 - 13791 (2018/09/14)
The newly discovered gold-catalysed reaction of isocyanides with hydrazoic acid generated in situ from trimethylsilyl azide and methanol (or, alternatively, from NaN3/AcOH) produces either cyanamides or 1-substituted 1H-tetrazol-5-amines, depending on the amount of available HN3. The reaction proceeds selectively and in generally high yields of either product, thus providing a particularly convenient access to a wide range of substituted 1H-tetrazol-5-amines that are rather difficult to access otherwise.