157920-22-4

Usage

Uses

Used in Fragrance Industry:
4-Pentenoic acid, 2-hydroxy-, ethyl ester is used as a fragrance ingredient for its fruity, floral, and slightly spicy scent, enhancing the aroma profiles of perfumes, colognes, and other scented products.
Used in Flavor Industry:
In the flavor industry, 4-Pentenoic acid, 2-hydroxy-, ethyl ester is used as a flavoring agent in food and beverage products, adding a unique taste and aroma to various consumables.
Used in Pharmaceutical Industry:
4-Pentenoic acid, 2-hydroxy-, ethyl ester has potential applications in the pharmaceutical industry, where its properties may be utilized for developing new drugs or improving drug delivery systems.
Used in Cosmetic Industry:
4-Pentenoic acid, 2-hydroxy-, ethyl ester is also used in the cosmetic industry, where it can contribute to the scent and texture of various cosmetic products, enhancing their appeal and effectiveness.
Overall, 4-Pentenoic acid, 2-hydroxy-, ethyl ester is a versatile compound valued for its pleasant smell and diverse applications across multiple commercial industries.

Upstream product

• 924-44-7 glyoxylic acid ethyl ester 
• 106-95-6 allyl bromide 
• 762-72-1 allyl-trimethyl-silane 
• 24850-33-7 allyltributylstanane 

Downstream Products

• 69778-57-0 2-(benzyloxy)pent-4-en-1-ol 
• 206348-80-3 Benzoic acid (R)-1-[dimethyl-(1,1,2-trimethyl-propyl)-silanyloxymethyl]-but-3-enyl ester 
• 206348-91-6 Benzoic acid (S)-1-[dimethyl-(1,1,2-trimethyl-propyl)-silanyloxymethyl]-but-3-enyl ester 
• 206348-92-7 (S)-1-hydroxypent-4-en-2-yl benzoate 

Relevant academic research and scientific papers

Fructose 1,6-bisphosphate aldolase from Staphylococcus carnosus: Overexpression, structure prediction, stereoselectivity, and application in the synthesis of bicyclic sugars

The gene for the fructose 1,6-bisphosphate aldolase from Staphylococcus carnosus (FruA(sca)) was subcloned for overexpression in Escherichia coli using the expression vector pKK223-3. An efficient, single-step purification by DEAE ion-exchange chromatography furnished the recombinant enzyme ready for synthetic applications. Sequence analysis indicated that FruA(sca) shares the overall α/β-barrel structure and most of the active site residues with the structurally well-defined FruA catalyst from rabbit muscle which signaled its functional equivalence for synthetic applications. A preparative study with generic aliphatic and hydroxylated aldehydes indeed confirmed a high level of stereoselectivity for both newly created asymmetric centers, and suggested a kinetic enantioselectivity for anionically charged 3- hydroxyaldehydes. In fact, the monomeric FruA(sca) was found to tolerate even the presence of highly reactive glutardialdehyde derivatives, which otherwise rapidly denature the rabbit muscle enzyme, and to allow their stereoselective conversion to bicyclic sugars.

From the North Sea to Drug Repurposing, the Antiseizure Activity of Halimide and Plinabulin

PharmaSea performed large-scale in vivo screening of marine natural product (MNP) ex-tracts, using zebrafish embryos and larvae, to identify compounds with the potential to treat epilepsy. In this study, we report the discovery of two new antiseizure comp

HETEROARYLDIHYDROPYRIMIDINE DERIVATIVES AND METHODS OF TREATING HEPATITIS B INFECTIONS

Provided herein are compounds useful for the treatment of HBV infection in a subject in need thereof, pharmaceutical compositions thereof, and methods of inhibiting, suppressing, or preventing HBV infection in the subject.

SPIRO-OXAZOLONES

The present invention provides spiro-oxazolones, which act as V1a receptor modulators, and in particular as V1a receptor antagonists, their manufacture, pharmaceutical compositions containing them and their use as medicaments. The present compounds are useful as therapeutics acting peripherally and centrally in the conditions of inappropriate secretion of vasopressin, anxiety, depressive disorders, obsessive compulsive disorder, autistic spectrum disorders, schizophrenia, aggressive behavior and phase shift sleep disorders, in particular jetlag.

Lewis acid catalyzed synthesis of cyclic carbonates, precursors of 1,2- and 1,3-diols

An eco-friendly synthesis of cyclic carbonates through a Lewis acid catalyzed cyclization of tert-butyl carbonates is described. These cyclic carbonates are precursors of 1,2- and 1,3-diols, and the developed method was applied to a short synthesis of a diarylheptanoid, (3S,5S)-alpinikatin.

FeCl3·6H2O, a catalyst for the diastereoselective synthesis of cis-isoxazolidines from N-protected δ-hydroxylamino allylic acetates

An ecofriendly and diastereoselective synthesis of cis-3,5-disubstituted isoxazolidines through the FeCl3·6H2O-catalyzed cyclization of δ-hydroxylamino allylic acetates is described. The synthetic potential of these products is highlighted by the preparation of several functionalized 1,3-amino alcohol precursors.

Radical cyclization of α-bromo aluminum acetals onto alkenes and alkynes (radic[al] process): A simple access to γ-lactols and 4-methylene-γ-lactols

An efficient preparation of γ-lactols and methylene-γ-lactols is described. Highly acid-sensitive lactols are prepared in a concise manner by using a radical cyclization of aluminum acetals. The precursors for the radical reactions are readily prepared fr

Dynamic kinetic resolution of α-substituted β-ketoesters catalyzed by Baeyer-Villiger monooxygenases: Access to enantiopure α-hydroxy esters

BVMOs make a play: The dynamic kinetic resolution of racemic α-alkyl-β-ketoesters was performed through a selective Baeyer-Villiger oxidation employing different Baeyer-Villiger monooxygenases (BVMOs) in mild basic media. The product diesters were obtained with excellent yields and enantioselectivities, and used as precursors for optically active α-hydroxy esters.

Construction of carbo- And heterocycles using radical relay cyclizations initiated by alkoxy radicals

An efficient method for the rapid construction of carbo- and heterocycles has been developed using radical relay cyclizations initiated by alkoxy radicals. Linear substrates were cyclized to form a wide range of cyclopentane, pyrrolidine, tetrahydropyran, and tetrahydrofuran derivatives in excellent yields. This methodology was utilized as a key step in the synthesis of the tetrahydrofuran fragment in (-)-amphidino-lide K.

Bis(NHC)-Pd(II) complexes as highly efficient catalysts for allylation of aldehydes with allyltributyltin

Novel cis-chelated bidentate bis(NHC)-Pd(II) complexes derived from 1,1′-binaphthyl-2,2′-diamine (BINAM) bearing weakly coordinating acetate or trifluoroacetate counterions have been synthesized and their structures have been characterized by X-ray diffra