206348-92-7Relevant academic research and scientific papers
Diphenylprolinol silyl ether as a catalyst in an asymmetric, catalytic and direct α-benzoyloxylation of aldehydes
Gotoh, Hiroaki,Hayashi, Yujiro
supporting information; experimental part, p. 3083 - 3085 (2009/12/01)
Diphenylprolinol silyl ether was found to promote asymmetric, catalytic and direct α-benzoyloxylation of aldehydes with benzoyl peroxide to afford oxidized products in good yields with excellent enantioselectivity. The Royal Society of Chemistry 2009.
Organocatalytic α-oxybenzoylation of aldehydes
Vaismaa, Matti J.P.,Yau, Sze Chak,Tomkinson, Nicholas C.O.
scheme or table, p. 3625 - 3627 (2009/09/30)
A simple method for the asymmetric α-oxybenzoylation of aldehydes is presented. Treatment of a series of aldehydes with benzoyl peroxide in the presence of a MacMillan imidazolidinone leads directly to the α-oxybenzoylated product with excellent levels of
A novel chiral synthetic equivalent of glyoxal and its application to the asymmetric synthesis of O-protected α-hydroxy aldehydes
Colombo,Di Giacomo
, p. 1977 - 1980 (2007/10/03)
Diastereomerically pure 2-formyl-N-Boc-1,3-oxazolidine 7 was prepared in 83% yield from stannyloxazolidine 4. Grignard additions to the formyl group of compound 7 in the presence of Lewis acids afforded diastereomerically pure secondary carbinols 8. Protection of the hydroxyl group and unmasking of the oxazolidine ring gave O-protected α-hydroxy aldehydes 11, which were immediately reduced to the corresponding 1,2-diols 12.
Chemoenzymatic synthesis of glycosylated enantiomerically pure 4- pentene 1,2- and 1,3-diol derivatives
Bien, Frank,Ziegler, Thomas
, p. 781 - 790 (2007/10/03)
1-Dimethylthexylsiloxy-2-chloroacetoxy-4-pentene 2 and 1- dimethylthexylsiloxy-3-chloroacetoxy-4-pentene 3 were saponified with Pseudomonas lipase to give (R)-1-dimethylthexylsiloxy-4-pentene-2-ol (ee=99%) and (S)-2 (ee=99%) and (S)-1-dimethylthexylsiloxy
