157948-03-3

Basic information

• Product Name: (+/-)-1-<2-(methylamino)-2-(4-nitrophenyl)ethyl>pyrrolidine
• Synonyms: (+/-)-1-<2-(methylamino)-2-(4-nitrophenyl)ethyl>pyrrolidine
• CAS NO: 157948-03-3
• Molecular Weight: 249.313
• Mol File: 157948-03-3.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: (+/-)-1-<2-(methylamino)-2-(4-nitrophenyl)ethyl>pyrrolidine(CAS DataBase Reference)
• NIST Chemistry Reference: (+/-)-1-<2-(methylamino)-2-(4-nitrophenyl)ethyl>pyrrolidine(157948-03-3)
• EPA Substance Registry System: (+/-)-1-<2-(methylamino)-2-(4-nitrophenyl)ethyl>pyrrolidine(157948-03-3)

Safety Data

• Hazardous Substances Data: 157948-03-3(Hazardous Substances Data)

Upstream product

• 158059-83-7 1-<2-(4-nitrophenyl)-2-aminoethyl>pyrrolidine 
• 14181-73-8 α-bromomethyl p-nitrophenyl ketoxime 
• 192188-01-5 (+/-)-N-(methoxycarbonyl)-2-(4-nitrophenyl)glycine 
• 5407-25-0 2-amino-2-(4-nitrophenyl)acetic acid 
• 192188-04-8 (+/-)-methyl N-<(4-nitrophenyl)(1-pyrrolidinylcarbonyl)methyl>carbamate 
• 157948-02-2 1-<2-(4-nitrophenyl)-2-formamidoethyl>pyrrolidine 

Downstream Products

• 157947-97-2 N-methyl-N-<(1S)-1-(4-nitrophenyl)-2-(1-pyrrolidinyl)ethyl>-3,4-dichlorophenylacetamide 
• 157948-07-7 N-methyl-N-<(1S)-1-(4-aminophenyl)-2-(1-pyrrolidinyl)ethyl>-3,4-dichlorophenylacetamide 
• 158059-82-6 1-<(2R)-2-(4-nitrophenyl)-2-(methylamino)ethyl>pyrrolidine 
• 158059-81-5 1-<(2S)-2-(4-nitrophenyl)-2-(methylamino)ethyl>pyrrolidine 
• 130109-60-3 2-(3,4-dichlorophenyl)-N-methyl-N-<(1R,S)-1-(4-aminophenyl)-2-(1-pyrrolidinyl)ethyl>acetamide 
• 130109-48-7 2-(3,4-dichlorophenyl)-N-methyl-N-<(1R,S)-1-(4-nitrophenyl)-2-(1-pyrrolidinyl)ethyl>acetamide 
• 157948-04-4 N-methyl-N-<(1S)-1-(4-nitrophenyl)-2-(1-pyrrolidinyl)ethyl>-(S)-α-acetoxyphenylacetamide 

Relevant articles and documents

Kappa opioid receptor agonists

The invention provides certain amino acid conjugates of substituted 2-phenyl-N-[1-(phenyl)-2-(1-heterocycloalkyl- or heterocycloaryl-)ethyl]acetamides useful for selectively agonizing kappa opioid receptors in mammalian tissue.

κ Opioid Receptor Selective Affinity Labels: Electrophilic Benzeneacetamides as κ-Selective Opioid Antagonists

2-(3,4-Dichlorophenyl)-N-methyl-N-acetamides 3-6 were synthesized as κ-selective affinity labels and evaluated for opioid activity.In smooth muscle preparations, the non-electrophilic parent compound