192188-01-5Relevant academic research and scientific papers
κ Opioid Receptor Selective Affinity Labels: Electrophilic Benzeneacetamides as κ-Selective Opioid Antagonists
Chang, An-Chih,Takemori, Akira E.,Ojala, William H.,Gleason, William B.,Portoghese, Philip S.
, p. 4490 - 4498 (1994)
2-(3,4-Dichlorophenyl)-N-methyl-N-acetamides 3-6 were synthesized as κ-selective affinity labels and evaluated for opioid activity.In smooth muscle preparations, the non-electrophilic parent compound
Kappa opioid receptor agonists
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, (2008/06/13)
The invention provides certain amino acid conjugates of substituted 2-phenyl-N-[1-(phenyl)-2-(1-heterocycloalkyl- or heterocycloaryl-)ethyl]acetamides useful for selectively agonizing kappa opioid receptors in mammalian tissue.
