15795-61-6Relevant articles and documents
Copper-catalysed domino reaction of 2-bromobenzylidenemalonates and 1,3-dicarbonyls for the synthesis of chromenes
Saebang, Yotsakorn,Rukachaisirikul, Vatcharin,Kaeobamrung, Juthanat
, p. 168 - 171 (2017)
4H-Chromenes were synthesized from 2-bromobenzylidenemalonates and 1,3-dicarbonyls under mild and simple reaction conditions via copper-catalysed domino reactions involving Michael addition and intramolecular Ullmann-type C(aryl)–O bond formation. Althoug
A practical and convenient protocol for the synthesis of (E)-α,β-unsaturated acids
Mohite, Amar R.,Bhat, Ramakrishna G.
supporting information, p. 4564 - 4567 (2013/09/24)
α,β-Unsaturated acids are very useful and versatile reagents in organic synthesis. A novel, practical, and convenient catalytic protocol comprising FeCl3·6H2O (0.5 mol %) and H 2O (1 equiv) in CH3NO2 is described for the rapid synthesis of α,β-unsaturated acids with high E-stereoselectivity under both microwave and conventional heating conditions with high TON and TOF values. This powerful approach efficiently demonstrated the utility of biomass derived aldehydes to build chemical agents used as fuel additives. The method proved to be scalable to gram scale synthesis.
A general and practical preparation of alkylidene Meldrum's acids
Dumas, Aaron M.,Seed, Adam,Zorzitto, Alexander K.,Fillion, Eric
, p. 7072 - 7074 (2008/03/11)
Although many methods have been reported for the Knoevenagel condensation of aldehydes and Meldrum's acid, most are not general or use unconventional reagents and conditions. We have found that alkylidene Meldrum's acids form readily in benzene solution u
