158038-38-1

Basic information

• Product Name: (2S,3R)-2-(tert-Butyl-diphenyl-silanyloxymethyl)-3-phenyl-pyrrolidine-1-carboxylic acid tert-butyl ester
• CAS NO: 158038-38-1
• Molecular Weight: 515.768
• Mol File: 158038-38-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (2S,3R)-2-(tert-Butyl-diphenyl-silanyloxymethyl)-3-phenyl-pyrrolidine-1-carboxylic acid tert-butyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (2S,3R)-2-(tert-Butyl-diphenyl-silanyloxymethyl)-3-phenyl-pyrrolidine-1-carboxylic acid tert-butyl ester(158038-38-1)
• EPA Substance Registry System: (2S,3R)-2-(tert-Butyl-diphenyl-silanyloxymethyl)-3-phenyl-pyrrolidine-1-carboxylic acid tert-butyl ester(158038-38-1)

Safety Data

• Hazardous Substances Data: 158038-38-1(Hazardous Substances Data)

Upstream product

• 144564-13-6 4S,5S-1-t-butoxycarbonyl-5-t-butyldiphenylsiloxymethyl-4-phenylpyrrolidine-2-one 

Downstream Products

• 118758-48-8 (2S,3R)-3-phenyl-pyrrolidine-2-carboxylic acid 
• 123724-21-0 (2S,3R)-1-(tert-butoxycarbonyl)-3-phenylpyrrolidine-2-carboxylic acid 
• 700367-14-2 tert-butyl (2R,3R)-2-(hydroxymethyl)-3-phenylpyrrolidine-1-carboxylate 

Relevant articles and documents

Synthesis of Homochiral 3-Substituted Glutamic Acids and Prolines from Pyroglutamic Acid

Efficient syntheses of (2S,3S)-methylproline (5a) and (2S,3R)-phenylproline (5b) are described, starting from the readily available pyroglutaminol derivatives 2a and 2b via conjugate 1,4=addition of organocuprates to 1.Catalytic hydrogenation of 3 from th