144564-13-6

Basic information

• Product Name: 4S,5S-1-t-butoxycarbonyl-5-t-butyldiphenylsiloxymethyl-4-phenylpyrrolidine-2-one
• CAS NO: 144564-13-6
• Molecular Weight: 529.751
• Mol File: 144564-13-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4S,5S-1-t-butoxycarbonyl-5-t-butyldiphenylsiloxymethyl-4-phenylpyrrolidine-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: 4S,5S-1-t-butoxycarbonyl-5-t-butyldiphenylsiloxymethyl-4-phenylpyrrolidine-2-one(144564-13-6)
• EPA Substance Registry System: 4S,5S-1-t-butoxycarbonyl-5-t-butyldiphenylsiloxymethyl-4-phenylpyrrolidine-2-one(144564-13-6)

Safety Data

• Hazardous Substances Data: 144564-13-6(Hazardous Substances Data)

Upstream product

• 919349-69-2 (S)-5-(tert-Butyl-diphenyl-silanyloxymethyl)-2-oxo-3-phenylselanyl-pyrrolidine-1-carboxylic acid tert-butyl ester 
• 138629-30-8 (S)-tert-butyl 2-((tert-butyldiphenylsilyloxy)methyl)-5-oxopyrrolidine-1-carboxylate 
• 138871-58-6 (S)-2-(tert-butyl-diphenyl-silanyloxymethyl)-5-oxo-2,5-dihydro-pyrrole-1-carboxylic acid tert-butyl ester 
• 591-51-5 phenyllithium 

Downstream Products

• 158038-38-1 (2S,3R)-2-(tert-Butyl-diphenyl-silanyloxymethyl)-3-phenyl-pyrrolidine-1-carboxylic acid tert-butyl ester 
• 700367-14-2 tert-butyl (2R,3R)-2-(hydroxymethyl)-3-phenylpyrrolidine-1-carboxylate 
• 118758-48-8 (2S,3R)-3-phenyl-pyrrolidine-2-carboxylic acid 
• 123724-21-0 (2S,3R)-1-(tert-butoxycarbonyl)-3-phenylpyrrolidine-2-carboxylic acid 

Relevant articles and documents

Synthesis of Homochiral R-Baclofen from S-Glutamic Acid

A streoselective synthesis of R-Baclofen is presented starting from S-pyroglutamic acid derivative 3.The key steps are the 1,4-conjugate addition of Grignard cuprate (p-ClPh)2CuMgCl to 3 and Barton-Decarboxylation of 6e to 7e.