1580503-38-3Relevant academic research and scientific papers
A General CuCl2-Promoted Alkene Aminochlorination Reaction
Li, Shu-Qi,Xiong, Peng,Zhu, Lin,Qian, Xiang-Yang,Xu, Hai-Chao
, p. 3449 - 3455 (2016)
A CuCl2-promoted alkene aminochlorination reaction has been developed. A variety of anilides that contain a mono-, di-, or trisubstituted alkenyl moiety readily participated in this reaction to afford structurally diverse vicinal chloroamines. Studies suggest that the process proceeds by a radical-type mechanism and that CuCl2serves as both the oxidant to generate the amidyl radical as well as the chloride source.
PdCl2 catalyzed efficient assembly of organic azides, CO, and alcohols under mild conditions: A direct approach to synthesize carbamates
Ren, Long,Jiao, Ning
, p. 3706 - 3709 (2014/04/03)
A simple and readily available PdCl2 catalyzed carbamate synthesis method via isocyanate generation and application in situ has been developed. This chemistry provides an efficient and practical approach to synthesize carbamates from simple organic azides, CO atmosphere and alcohols. The broad scope, mild and neutral conditions, and only N2 as the byproduct make this transformation very useful. Moreover, simple examples of modification of bioactive molecules and construction of macrocycles were achieved through this protocol. This journal is the Partner Organisations 2014.
