1581275-72-0Relevant academic research and scientific papers
Exploiting the 4-Phenylquinazoline Scaffold for the Development of High Affinity Fluorescent Probes for the Translocator Protein (TSPO)
Milite, Ciro,Barresi, Elisabetta,Da Pozzo, Eleonora,Costa, Barbara,Viviano, Monica,Porta, Amalia,Messere, Anna,Sbardella, Gianluca,Da Settimo, Federico,Novellino, Ettore,Cosconati, Sandro,Castellano, Sabrina,Taliani, Sabrina,Martini, Claudia
, p. 7897 - 7909 (2017/10/06)
The quinazoline class was exploited to search for a new translocator protein (TSPO) fluorescent probe endowed with improved affinity and residence time (RT). Computational studies on an "in-house" collection of quinazoline derivatives, featuring highly st
Structure-activity relationship refinement and further assessment of 4-phenylquinazoline-2-carboxamide translocator protein ligands as antiproliferative agents in human glioblastoma tumors
Castellano, Sabrina,Taliani, Sabrina,Viviano, Monica,Milite, Ciro,Da Pozzo, Eleonora,Costa, Barbara,Barresi, Elisabetta,Bruno, Agostino,Cosconati, Sandro,Marinelli, Luciana,Greco, Giovanni,Novellino, Ettore,Sbardella, Gianluca,Da Settimo, Federico,Martini, Claudia
, p. 2413 - 2428 (2014/04/17)
Structure-activity relationships (SARs) within the 4-phenylquinazoline-2- carboxamide series of translocator protein (TSPO) ligands have been explored further by the synthesis and TSPO binding affinity evaluation of N-benzyl-N-ethyl/methyl derivatives var
