158147-91-2Relevant academic research and scientific papers
Quinolizidines. XXXIII. A chiral synthesis of (-)-ophiorrhizine, a pentacyclic quaternary indole alkaloid from ophiorrhiza major RIDL
Fujii,Ohba,Seto
, p. 49 - 52 (2007/10/02)
A detailed account is given of the first chiral synthesis of the Ophiorrhiza alkaloid ophiorrhizine [(-)-1]. The synthesis was started by coupling the lactim ether (+)-4, readily available from cincholoipon ethyl ester [(+)-3], with 6-benzyloxy-3-chloroac
Absolute Stereochemistry of the Pentacyclic Quaternary Indole Alkaloid Ophiorrhizine: Synthetic Incorporation of Cincholoipon Ethyl Ester Into (-)-Ophiorrhizine
Ohba, Masashi,Seto, Shigeki,Fujii, Tozo,Sargent, Melvyn V.,Arbain, Dayar
, p. 1741 - 1744 (2007/10/02)
The absolute stereochemistry of the Ophiorrhiza alkaloid ophiorrhizine has been defined as shown in formula by a chemical correlation with the Cinchona alkaloid cinchonine through cincholoipon ethyl ester and the lacitim ether .The
