158147-87-6

Upstream product

• 96790-30-6 (3R,4R)-(+)-6-ethoxy-3-ethyl-2,3,4,5-tetrahydro-4-pyridineacetic acid ethyl ester 
• 116725-92-9 1-(6-benzyloxy-1H-indol-3-yl)-2-chloroethanone 
• 15903-94-3 6-benzyloxy-1H-indole 

Downstream Products

• 158147-92-3 11-benzyloxycorynan-17-ol 
• 158147-91-2 11-benzyloxycorynan-17-oic acid ethyl ester 
• 158147-88-7 (4R,54R)-1-<2-(6-benzyloxy-1H-indol-3-yl)ethyl>-5-ethyl-2-oxo-4-piperidineacetic acid ethyl ester 
• 158147-93-4 Toluene-4-sulfonic acid 2-((2R,3R,12bS)-10-benzyloxy-3-ethyl-1,2,3,4,6,7,12,12b-octahydro-indolo[2,3-a]quinolizin-2-yl)-ethyl ester 

Relevant academic research and scientific papers

Quinolizidines. XXXIII. A chiral synthesis of (-)-ophiorrhizine, a pentacyclic quaternary indole alkaloid from ophiorrhiza major RIDL

A detailed account is given of the first chiral synthesis of the Ophiorrhiza alkaloid ophiorrhizine [(-)-1]. The synthesis was started by coupling the lactim ether (+)-4, readily available from cincholoipon ethyl ester [(+)-3], with 6-benzyloxy-3-chloroac

Absolute Stereochemistry of the Pentacyclic Quaternary Indole Alkaloid Ophiorrhizine: Synthetic Incorporation of Cincholoipon Ethyl Ester Into (-)-Ophiorrhizine

The absolute stereochemistry of the Ophiorrhiza alkaloid ophiorrhizine has been defined as shown in formula by a chemical correlation with the Cinchona alkaloid cinchonine through cincholoipon ethyl ester and the lacitim ether .The