158149-97-4

Upstream product

• 188183-31-5 (2RS)-(1S,2R,4R)-10-(Dicyclohexylsulfamoyl)isobornyl 3-phenyl-2-cyanopropanoate 

Downstream Products

• 158149-99-6 (S)-α,β-diamino-α-benzyl-propionic acid 
• 158149-98-5 (S)-2-Amino-2-aminomethyl-3-phenyl-propionic acid (1S,2R,4R)-1-[(dicyclohexylsulfamoyl)-methyl]-7,7-dimethyl-bicyclo[2.2.1]hept-2-yl ester 

Relevant academic research and scientific papers

Stereoselective Amination of Chiral Enolates: Synthesis of enantiomerically pure α,β-Diamino Acids, Chiral Key Compounds in the Synthesis of Conformationally Constrained Peptido- and Non-peptidomimetics

This work describes an efficient synthesis of enantiomerically pure (R)-2-aminomethylalanine, (R)-2-aminomethylnorvaline, (R)-2-aminomethylvaline, (R)-2-aminomethylleucine and (R)-2-aminomethylphenylalanine by electrophilic amination of chiral 2-cyanoeste

Stereoselective Amination of Chiral Enolates: Synthesis of Chiral Key Intermediates for β-Lactam Antibiotics

Stereoselective enolate trapping of lithium (1S,2R,4R)-1O-dicyclohexylsulfamoylisobornyl-2-cyano-3-phenylpropanoate with O-(diphenylphosphinyl)hydroxylamine followed by appropriate reduction, hydrolysis, and cyclisation processes allows the asymmetric syn