158211-98-4

Upstream product

• 1258503-65-9 C₁₅H₂₂N₂O₄ 
• 195510-33-9 (2R,3S)-3-(dibenzylamino)-2-hydroxy-4-phenylbutanoic acid 
• 859403-78-4 (2R,3S)-3-Dibenzylamino-2-hydroxy-4-phenyl-butyramide 

Downstream Products

• 859404-09-4 3-Ethyl-4-oxo-4H-chromene-2-carboxylic acid ((1S,2R)-1-benzyl-2-carbamoyl-2-hydroxy-ethyl)-amide 
• 859404-07-2 7-Methyl-8-oxo-2,3-dihydro-8H-1,4,5-trioxa-anthracene-6-carboxylic acid ((1S,2R)-1-benzyl-2-carbamoyl-2-hydroxy-ethyl)-amide 
• 859404-05-0 3-Methyl-4-oxo-4H-chromene-2-carboxylic acid ((1S,2R)-1-benzyl-2-carbamoyl-2-hydroxy-ethyl)-amide 
• 1007566-98-4 C₂₁H₂₁N₃O₄ 
• 1298120-44-1 N-((2S,3R)-4-amino-3-hydroxy-4-oxo-1-phenylbutan-2-yl)-6,7-dimethoxy-3-methyl-4-oxo-4H-chromene-2-carboxamide 
• 1234915-64-0 C₃₄H₄₈N₆O₈ 
• 1234915-61-7 C₃₂H₄₅FN₈O₈ 
• 1234915-60-6 C₂₉H₄₄N₁₀O₆ 
• 1234915-59-3 C₃₁H₄₄N₆O₈ 
• 1234915-58-2 C₂₉H₄₁FN₈O₈ 
• 1234915-56-0 C₂₆H₄₀N₁₀O₆ 

Relevant academic research and scientific papers

Tetrapeptides, as small-sized peptidic inhibitors; synthesis and their inhibitory activity against BACE1

β-Site amyloid precursor protein cleaving enzyme 1 (BACE1) is known to be involved in the production of amyloid β-peptide in Alzheimer's disease and is a major target for current drug design. We previously reported substrate-based peptidomimetics, KMI-com

Synthesis and biological evaluation of chromone carboxamides as calpain inhibitors

Excessive calpain activations contribute to serious cellular damage and have been found in many pathological conditions. Novel chromone carboxamides derived from ketoamides were prepared and evaluated for μ-calpain inhibition. Among synthesized, compound