859404-09-4Relevant articles and documents
Synthesis and biological evaluation of chromone carboxamides as calpain inhibitors
Kwang, Seob Lee,Seon, Hee Seo,Yong, Ha Lee,Ha, Dong Kim,Moon, Ho Son,Bong, Young Chung,Jae, Yeol Lee,Jin, Changbae,Yong, Sup Lee
, p. 2857 - 2860 (2007/10/03)
Excessive calpain activations contribute to serious cellular damage and have been found in many pathological conditions. Novel chromone carboxamides derived from ketoamides were prepared and evaluated for μ-calpain inhibition. Among synthesized, compound