15827-56-2

Basic information

• Product Name: CIS-1,4-CYCLOHEXANEDIAMINE
• Synonyms: CIS-1,4-CYCLOHEXANEDIAMINE;CIS-1,4-DIAMINOCYCLOHEXANE;CI(S)-CYCLOHEXANE-1,4-DIAMINE;1,4-Cyclohexanediamine, cis-;cis-1,4-Cyclohexanediamine ,96%
• CAS NO: 15827-56-2
• Molecular Formula: C₆H₁₄N₂
• Molecular Weight: 114.19
• EINECS: 221-483-6
• Mol File: 15827-56-2.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 90 °C / 22mmHg
• Flash Point: 80 °C
• Appearance: /
• Density: 0.97
• Vapor Pressure: 0.342mmHg at 25°C
• Refractive Index: 1.4950-1.4990
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• PKA: 10.78±0.70(Predicted)
• CAS DataBase Reference: CIS-1,4-CYCLOHEXANEDIAMINE(CAS DataBase Reference)
• NIST Chemistry Reference: CIS-1,4-CYCLOHEXANEDIAMINE(15827-56-2)
• EPA Substance Registry System: CIS-1,4-CYCLOHEXANEDIAMINE(15827-56-2)

Safety Data

• Statements: 22-34
• Safety Statements: 26-36/37/39-45
• RIDADR: UN 3259PSN1 8 / PGII
• HazardClass: 8
• PackingGroup: III
• Hazardous Substances Data: 15827-56-2(Hazardous Substances Data)

Usage

Chemical Properties

Clear colorless liquid

InChI:InChI=1/C6H14N2/c7-5-1-2-6(8)4-3-5/h5-6H,1-4,7-8H2/t5-,6+

Upstream product

• 100-01-6 4-nitro-aniline 
• 637-88-7 1,4-Cyclohexanedione 
• 100-02-7 4-nitro-phenol 
• 3114-70-3 trans-1,4-diaminocyclohexane 
• 106-50-3 1,4-phenylenediamine 
• 556-48-9 1,4-Cyclohexanediol 
• 32222-08-5 cis-1.4-bis-methoxycarbonylamino-cyclohexane 

Downstream Products

• 181760-73-6 N-(5-Chloro-pyrimidin-2-yl)-N'-{4-[N'-(5-chloro-pyrimidin-2-yl)-guanidino]-cyclohexyl}-guanidine 
• 2840-91-7 cis-cyclohexane-1,4-diacetamide 
• 113282-19-2 cis-1,4-dibenzylideneaminocyclohexane 
• 61366-98-1 1-(2-Chloro-ethyl)-3-{4-[3-(2-chloro-ethyl)-ureido]-cyclohexyl}-urea 

Relevant articles and documents

The Rhodium Catalysed Direct Conversion of Phenols to Primary Cyclohexylamines

Cyclohexylamines are important intermediates in chemical industry, which are currently produced from petrochemical sources. Phenols, however, are an attractive sustainable feedstock. We here demonstrate the transformation of phenols with ammonia to primary cyclohexylamines. In contrast to previously reported chemistry which used palladium catalysts, we here show that rhodium is an excellent catalyst for the formation of primary cyclohexylamines. Different parameters were studied and it was shown that the reaction is applicable to a scope of phenolic compounds providing high selectivity.

Catalytic hydrogenation of 1,4-phenylenediamine to 1,4-cyclohexanediamine

Catalytic hydrogenation of 1,4-phenylenediamine to 1,4-cyclohexanediamine using Ru/Al2O3 as a catalyst was carried out in water, and the results were compared with those in isopropanol and SC-CO2. 80% 1,4-phenylenediamine conversion with 87% selectivity to 1,4-cyclohexanediamine was achieved on 5% Ru/Al2O3 catalyst at 90°C and H2 pressure of 4 MPa. The hydrogenation of 1,4-phenylenediamine is influenced by the solvent. A systematic study of the hydrogenation of 1,4-phenylenediamine revealed that the reaction was consecutive. The longer the time, the lower was the CHDA selectivity. Also, the reaction temperature was an important parameter and played a vital role in preventing the formation of side products. Pleiades Publishing, Ltd., 2014.