1582740-97-3

Basic information

• Product Name: C₁₉H₂₄O₃
• CAS NO: 1582740-97-3
• Molecular Weight: 300.398
• Mol File: 1582740-97-3.mol

Chemical Properties

• CAS DataBase Reference: C₁₉H₂₄O₃(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₉H₂₄O₃(1582740-97-3)
• EPA Substance Registry System: C₁₉H₂₄O₃(1582740-97-3)

Safety Data

• Hazardous Substances Data: 1582740-97-3(Hazardous Substances Data)

Upstream product

• 1582740-92-8 (S)-1-((2R,7R)-7-ethynyl-2,3,6,7-tetrahydrooxepin-2-yl)propan-1-ol 
• 50-00-0 formaldehyd 
• 1582740-94-0 (2R,7R)-2-((S)-1-(benzyloxy)propyl)-7-ethynyl-2,3,6,7-tetrahydrooxepine 
• 100-39-0 benzyl bromide 

Downstream Products

• 1582741-08-9 (S)-1-((2S,7R)-7-((S)-1-(benzyloxy)propyl)-2,3,6,7-tetrahydrooxepin-2-yl)propane-1,3-diol 
• 1582741-04-5 C₁₉H₂₆O₄ 
• 1582741-13-6 C₃₁H₅₆O₄Si₂ 
• 1582740-98-4 (E)-3-((2R,7R)-7-((S)-1-(benzyloxy)propyl)-2,3,6,7-tetrahydrooxepin-2-yl)prop-2-en-1-ol 

Relevant articles and documents

β-Hydroxy-γ-lactones as nucleophiles in the Nicholas reaction for the synthesis of oxepene rings. Enantioselective formal synthesis of (-)-isolaurepinnacin and (+)-rogioloxepane A

The enantioselective formal synthesis of (-)-isolaurepinnacin and (+)-rogioloxepane A has been achieved. The key steps are an intermolecular Nicholas reaction with a β-hydroxy-γ-lactone as the nucleophile, to form branched linear ethers, and an olefin ring-closing metathesis to obtain the oxepene core. This journal is the Partner Organisations 2014.