15834-60-3

Upstream product

• 2786-80-3 4-hydroxy-3,5-dimethoxyazobenzene 
• 6307-90-0 3,4,5-trimethoxy-1-nitrobenzene 
• 19978-25-7 3,5-dimethoxy-4-hydroxynitrobenzene 
• 91-10-1 1,3-dimethoxy-2-hydroxy-benzene 
• 73968-04-4 2,6-Dimethoxy-4-phenylazo-phenol 

Downstream Products

• 856859-13-7 1-(4-hydroxy-3,5-dimethoxy-phenyl)-2,6-dimethyl-4-oxo-1,4-dihydro-pyridine-3,5-dicarboxylic acid diethyl ester 
• 150563-56-7 Methyl <<5-acetoxy-2-(acetylamino)-4,6-dimethoxyphenyl>thio>acetate 
• 150563-55-6 4-(Acetylamino)-2,6-dimethoxy-3-thiocyanophenyl acetate 
• 150563-54-5 4-(Acetylamino)-2,6-dimethoxyphenyl acetate 

Relevant academic research and scientific papers

Design, synthesis, and biological evaluation of F-18-labelled 2, 4-diaminopyrimidine-type FAK-targeted inhibitors as potential tumour imaging agents

As a type of intracellular nonreceptor tyrosine kinase, focal adhesion kinase (FAK) can be highly expressed in most types of tumours and is thus regarded as a promising antitumour target. In this study, a series of novel 2,4-diaminopyrimidine FAK-targeted

Cellular apoptosis and cytotoxicity of phenolic compounds: A quantitative structure-activity relationship study

In this comprehensive study on the caspase-mediated apoptosis-inducing effect of 51 substituted phenols in a murine leukemia cell line (L1210), we determined the concentrations needed to induce caspase activity by 50% (I 50) and utilized these

SUBSTITUTED TRIAZINE COMPOUNDS AND USES THEREOF

The present invention relates to compounds of formula (I) : including any stereochemically isomeric form thereof, or pharmaceutically acceptable salts thereof, for the treatment of, for example, hypercholesterolemia.

Compound targeting FAK and marker thereof as well as preparation method and application thereof (by machine translation)

The invention provides a compound targeting FAK, the structure of which is shown by the following formula (I), wherein R is represented by the following formula (I). 1 - F, Cl, Br, CH3 OR-OCH3 ; R2 , R3/su

Pharmacophore Hybridization to Discover Novel Topoisomerase II Poisons with Promising Antiproliferative Activity

We used a pharmacophore hybridization strategy to combine key structural elements of merbarone and etoposide and generated new type II topoisomerase (topoII) poisons. This first set of hybrid topoII poisons shows promising antiproliferative activity on hu

5-CARBOXAMIDE-2-THIOBARBITURIC ACIDS AND USE THEREOF AS MEDICAMENTS

The invention relates to a class of 5-carboxamide-2-thiobarbituric acid derivatives which inhibits human type II topoisomerase (topoII) enzyme and to use thereof as medicaments especially for blocking the proliferation of cancer cells and treating cancer.