Welcome to LookChem.com Sign In|Join Free
  • or
(1R,2R,4R)-N-benzyl-1,7,7-trimethylbicyclo[2.2.1]heptan-2-amine is a chiral isobornylamine derivative that serves as an effective NMR chiral solvating agent for discriminating enantiomers of acids, particularly in the quantitative determination of enantiomeric excess and resolution of racemic mandelic acid. Its utility stems from its ability to form diastereomeric complexes with chiral acids, leading to distinct NMR signal shifts, as supported by X-ray crystallographic studies of its mandelate salts. (1R,2R,4R)-N-benzyl-1,7,7-trimethylbicyclo[2.2.1]heptan-2-amine's rigid bicyclic framework and stereochemistry enhance its chiral recognition capabilities.

158411-96-2

Post Buying Request

158411-96-2 Suppliers

Recommended suppliers

  • Product
  • FOB Price
  • Min.Order
  • Supply Ability
  • Supplier
  • Contact Supplier

158411-96-2 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 158411-96-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,5,8,4,1 and 1 respectively; the second part has 2 digits, 9 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 158411-96:
(8*1)+(7*5)+(6*8)+(5*4)+(4*1)+(3*1)+(2*9)+(1*6)=142
142 % 10 = 2
So 158411-96-2 is a valid CAS Registry Number.

158411-96-2Downstream Products

158411-96-2Relevant academic research and scientific papers

Benzyl isobornyl amines: a simple and practical class of NMR discriminating agents for effective chiral recognition of acids

Kannappan, Jayaraman,Khanvilkar, Aditya N.,Upadhyay, Gourav M.,Bedekar, Ashutosh V.

, p. 1297 - 1303 (2017)

The design and synthesis of a few simple N-benzyl derivatives of isobornyl amine is presented. The derivatives have been assessed as chiral solvating agents for effective discrimination of the signals of some acids in NMR analysis. The single crystal X-ray analysis of the salts of (R)-mandelic acid with two of the title derivatives help to understand the supramolecular interactions and assign the induced chemical shifts in 1H NMR analysis. The title derivative is found to be suitable for quantitative determination of the enantiomeric excess of unknown enantiomeric purity as well as being efficient in resolving racemic mandelic acid.

Direct Reductive Amination of Camphor Using Iron Pentacarbonyl as Stoichiometric Reducing Agent: Features and Limitations

Afanasyev, Oleg I.,Amangeldyev, Artem,Chusov, Denis,Fatkulin, Artemy R.,Semenov, Sergey E.,Smirnov, Ivan,Solyev, Pavel N.

, p. 6289 - 6294 (2020)

The method of direct reductive amination of camphor and fenchone was proposed. The most effective reducing agent is iron carbonyl. No ligands or solvents are needed. The stereochemistry of the corresponding products was determined by HMBC, HSQC, and NOESY

Metal-free diastereoselective catalytic hydrogenations of imines using B(C6F5)3

Heiden, Zachariah M.,Stephan, Douglas W.

, p. 5729 - 5731 (2011/07/08)

Reductions of chiral ketimines effected under H2 by catalytic amounts of B(C6F5)3 result in moderate to excellent diastereoselectivities. In the case of camphor and menthone derived imines, the reductions procee

Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1 Customer Service

What can I do for you?
Get Best Price

Get Best Price for 158411-96-2