1584139-23-0

Basic information

• Product Name: (2R,3S)-3-((1-fluorocyclobutyl)methyl)-N-((3S)-9-methyl-2-oxo-5-phenyl-2,3-dihydro-1H-1,4-benzodiazepin-3-yl)-2-(3,3,3-trifluoropropyl)succinamide
• Synonyms: (2R,3S)-3-((1-fluorocyclobutyl)methyl)-N-((3S)-9-methyl-2-oxo-5-phenyl-2,3-dihydro-1H-1,4-benzodiazepin-3-yl)-2-(3,3,3-trifluoropropyl)succinamide
• CAS NO: 1584139-23-0
• Molecular Weight: 546.565
• Mol File: 1584139-23-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (2R,3S)-3-((1-fluorocyclobutyl)methyl)-N-((3S)-9-methyl-2-oxo-5-phenyl-2,3-dihydro-1H-1,4-benzodiazepin-3-yl)-2-(3,3,3-trifluoropropyl)succinamide(CAS DataBase Reference)
• NIST Chemistry Reference: (2R,3S)-3-((1-fluorocyclobutyl)methyl)-N-((3S)-9-methyl-2-oxo-5-phenyl-2,3-dihydro-1H-1,4-benzodiazepin-3-yl)-2-(3,3,3-trifluoropropyl)succinamide(1584139-23-0)
• EPA Substance Registry System: (2R,3S)-3-((1-fluorocyclobutyl)methyl)-N-((3S)-9-methyl-2-oxo-5-phenyl-2,3-dihydro-1H-1,4-benzodiazepin-3-yl)-2-(3,3,3-trifluoropropyl)succinamide(1584139-23-0)

Safety Data

• Hazardous Substances Data: 1584139-23-0(Hazardous Substances Data)

Upstream product

• 1584139-32-1 (R)-tert-butyl 2-((S)-1-amino-3-(1-fluorocyclobutyl)-1-oxopropan-2-yl)-5,5,5-trifluoropentanoate 
• 1584139-93-4 (S)-benzyl (9-methyl-2-oxo-5-phenyl-2,3-dihydro-1H-benzo[e] [1,4]diazepin-3-yl)carbamate 
• 1584139-82-1 (S)-3-amino-9-methyl-5-phenyl-1H-benzo[e][1,4]diazepin-2(3H)-one 
• 1584139-34-3 (R)-2-((S)-1-amino-3-(1-fluorocyclobutyl)-1-oxopropan-2-yl)-5,5,5-trifluoropentanoic acid 
• 5054-32-0 (2-amino-3-methylphenyl)(phenyl)methanone 

Relevant articles and documents

FLUOROALKYL AND FLUOROCYCLOALKYL 1,4-BENZODIAZEPINONE COMPOUNDS AS NOTCH|INHIBITORS

Disclosed are compounds of Formula (I): (Formula (I)) wherein: R1 is -CH2CH2CF3; R2 is -CH2CH2CH2F, -CH2CF2CH3, -CH2CH