15845-62-2Relevant articles and documents
Water-Proton Relaxivities of Radical Nanoparticles Self-Assembled via Hydration or Dehydration Processes
Morishita, Kosuke,Okamoto, Yuna,Murayama, Shuhei,Usui, Kazuteru,Ohashi, Eriko,Hirai, Go,Aoki, Ichio,Karasawa, Satoru
, p. 7810 - 7817 (2017)
Nanoparticles capable of accumulating in tumor tissues are promising materials for tumor imaging and therapy. In this study, two radical nanoparticles (RNPs), denoted as 1 and 2, composed of self-assembled ureabenzene derivatives possessing one or two amp
Electrochemically Enabled Intramolecular Aminooxygenation of Alkynes via Amidyl Radical Cyclization
Hou, Zhong-Wei,Xu, Hai-Chao
supporting information, p. 394 - 398 (2020/03/04)
An electrochemical synthesis of oxazol-2-ones and imidazol-2-ones has been developed via 5-exo-dig cyclization of propargylic carbamates- and ureas-derived amidyl radicals. The electrosynthesis relies on the dual function of 2,2,6,6-tetramethylpiperidin- 1-yl)oxyl (TEMPO) as a redox mediator for amidyl radical formation and an oxygen atom donor. The reactions are conducted under mild conditions using a simple setup and provide convenient access to functionalized oxazol-2-ones and imidazol-2-ones from readily available materials.
Electrochemical C?H/N?H Functionalization for the Synthesis of Highly Functionalized (Aza)indoles
Hou, Zhong-Wei,Mao, Zhong-Yi,Zhao, Huai-Bo,Melcamu, Yared Yohannes,Lu, Xin,Song, Jinshuai,Xu, Hai-Chao
supporting information, p. 9168 - 9172 (2016/08/05)
Indoles and azaindoles are among the most important heterocycles because of their prevalence in nature and their broad utility in pharmaceutical industry. Reported herein is an unprecedented noble-metal- and oxidant-free electrochemical method for the coupling of (hetero)arylamines with tethered alkynes to synthesize highly functionalized indoles, as well as the more challenging azaindoles.