1585154-09-1

Basic information

• Product Name: C₅₈H₈₄O₂₀
• Synonyms: C₅₈H₈₄O₂₀
• CAS NO: 1585154-09-1
• Molecular Weight: 1101.29
• Mol File: 1585154-09-1.mol

Chemical Properties

• CAS DataBase Reference: C₅₈H₈₄O₂₀(CAS DataBase Reference)
• NIST Chemistry Reference: C₅₈H₈₄O₂₀(1585154-09-1)
• EPA Substance Registry System: C₅₈H₈₄O₂₀(1585154-09-1)

Safety Data

• Hazardous Substances Data: 1585154-09-1(Hazardous Substances Data)

Upstream product

• 119301-59-6 tetra(p-hydroxyphenyl)ethylene 
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• 136399-06-9 2-(2-(2-(2-iodoethoxy)ethoxy)ethoxy)ethanol 
• 112-60-7 Tetraethylene glycol 
• 65883-12-7 2-{2-[2-(2-hydroxyethoxy)ethoxy]ethoxy}ethyl methanesulfonate 

Relevant articles and documents

Synthesis of a series of ethylene glycol modified water-soluble tetrameric TPE-amphiphiles with pyridinium polar heads: Towards applications as light-up bioprobes in protein and DNA assay, and wash-free imaging of bacteria

Available online Development of water soluble AIE-active “light-up” bioprobes for the detection of biomacromolecules has drawn huge research interests in recent past. In this study, a series of ethylene glycol modified water soluble tetrameric tetraphenyl

Supramolecular enhancement of aggregation-induced emission and its application in cancer cell imaging

Compared with conventional fluorophores which are often quenched in the aggregate state or at high concentration due to concentration quenching or aggregation-caused quenching, tetraphenylethene (TPE)-based organic fluorogens exhibit an extraordinary aggregation-induced emission (AIE) feature, providing a new platform for the development of fluorescence light-up molecules and photostable nanoaggregates for specific analyte detection and imaging. However, self-assembly of TPE-based building blocks can hardly be achieved without introduction of other driving forces due to the propeller-shaped structure and the dynamic rotation of the phenyl rings of the TPE unit. Herein, two four-armed TPE derivatives containing electron-rich naphthalene (TPE-NP) and electron-deficient paraquat (TPE-PQ) groups, respectively, were designed and synthesized. Driven by charge-transfer (CT) interactions, a complex formed between TPE-NP and TPE-PQ. It self-assembled into nanorods in a 1D packing mode, resulting in the restriction of intramolecular rotation to enhance the AIE effect significantly. A difunctional negatively charged water-soluble pillar[6]arene (H) was used to reduce the toxicity of TPE-PQ by forming a stable inclusion complex (H4?TPE-PQ) with TPE-PQ. A ternary system containing H, TPE-NP and TPE-PQ was utilized as an imaging agent for cancer cells due to the pH-responsiveness of H. Compared to the physiological pH of 7.4, the pH in tumor tissue and endosomes is more acidic, resulting in the disassembly of the host-guest complex H4?TPE-PQ and the formation of the AIE-enhanced CT complex between TPE-NP and TPE-NP in cancer cells. This journal is the Partner Organisations 2014.

Monomer emission and aggregate emission of TPE derivatives in the presence of γ-cyclodextrin

It was found for the first time that neutral amphiphilc tetraphenylethylene (TPE) derivatives showed an enhanced monomer emission and a decreased aggregate emission when they were included in the cavity of γ-cyclodextrin. This result provided a new insight into the aggregation-induced emission (AIE) effect.