1585185-72-3Relevant articles and documents
Palladium-catalyzed cyclization of vinyl iodide-tethered allensulfonamide
Xie, Zheng,Wu, Pan,Cai, Liangzhen,Tong, Xiaofeng
, p. 2160 - 2162 (2014/04/03)
This Letter describes a palladium-catalyzed cyclization of vinyl iodide-tethered allensulfonamide in the presence of alkylol, which provides a facile access to 2-alkoxy-3-methylene-tetrahydropyridine. The asymmetric version of this reaction has also been preliminarily realized with up to 81% enantioselectivity when chiral bisphosphine ligands were used.