158531-91-0

Upstream product

• 107-21-1 ethylene glycol 
• 158531-90-9 (R)-(+)-2-((Phenylthio)methyl)-2-(3,4-dimethoxyphenyl)cyclobutanone 
• 158531-87-4 1-(tert-Butyldiphenylsiloxy)-2-cyclopropylidene-2-(3,4-dimethoxyphenyl)ethane 
• 158531-86-3 (tert-Butyldiphenylsiloxy)methyl 3,4-dimethoxyphenyl ketone 
• 158531-89-6 (S)-(-)-2-(Hydroxymethyl)-2-(3,4-dimethoxyphenyl)cyclobutanone 
• 158531-88-5 2-Cyclopropylidene-2-(3,4-dimethoxyphenyl)ethanol 
• 89980-69-8 3,4-dimethoxyphenylmagnesium bromide 

Downstream Products

• 158531-97-6 (2S)-(-)-2-(3-Buten-1-yl)-2-(3,4-dimethoxyphenyl)cyclobutanone 

Relevant academic research and scientific papers

A Highly Enantiocontrolled Strategy for the Synthesis of Benzylic Quaternary Carbon Centers. A Formal Total Synthesis of (-)-Mesebrine

A remarkable substituent effect by a trimethylsilyl group was observed on the enantioselectivity of the tandem asymmetric epoxidation and enantiospecific ring expansion of 2-cyclopropylidene-2-(4,5-dimethoxy-2-(trimethylsilyl)phenyl)ethanol (24), affordin

An Asymmetric Synthesis of Benzylic Quaternary Carbon Centers. A Formal Total Synthesis of (-)-Mesembrine

The optically pure sulfone 15, prepared by tandem asymmetric epoxidation and 1,2-rearrangement of the cyclopropylideneethanol 11 as a key step, was converted into the olefinic cyclobutanone 20 which was then transformed into the ketonic lactone 22 via the