15865-96-0

Basic information

• Product Name: 4-METHYL-2-PHENYLAMINO-THIAZOLE-5-CARBOXYLIC ACID ETHYL ESTER
• Synonyms: ethyl 4-methyl-2-(phenylamino)thiazole-5-carboxylate;ethyl 2-anilino-4-methyl-1,3-thiazole-5-carboxylate
• CAS NO: 15865-96-0
• Molecular Formula: C₁₃H₁₄N₂O₂S
• Molecular Weight: 262.33
• Mol File: 15865-96-0.mol
• Article Data: 5

Chemical Properties

• Melting Point: 98 °C(Solv: ethanol, 50% (64-17-5))
• Boiling Point: 390.1±34.0 °C(Predicted)
• Appearance: /
• Density: 1.256±0.06 g/cm3(Predicted)
• PKA: 3.41±0.10(Predicted)
• CAS DataBase Reference: 4-METHYL-2-PHENYLAMINO-THIAZOLE-5-CARBOXYLIC ACID ETHYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: 4-METHYL-2-PHENYLAMINO-THIAZOLE-5-CARBOXYLIC ACID ETHYL ESTER(15865-96-0)
• EPA Substance Registry System: 4-METHYL-2-PHENYLAMINO-THIAZOLE-5-CARBOXYLIC ACID ETHYL ESTER(15865-96-0)

Safety Data

• Hazardous Substances Data: 15865-96-0(Hazardous Substances Data)

Upstream product

• 141-97-9 ethyl acetoacetate 
• 103-85-5 monophenylthiourea 
• 609-15-4 ethyl 2-chloro-3-oxo-butyrate 
• 98949-67-8 N-phenylthiocarbamoylacetamidine 
• 103-72-0 phenyl isothiocyanate 

Downstream Products

• 436094-60-9 4-methyl-2-(N-phenylamino)thiazole-5-carboxylic acid 
• 952394-97-7 2-(tert-butoxycarbonyl-phenyl-amino)-4-methyl-thiazole-5-carboxylic acid ethyl ester 

Relevant articles and documents

One-Pot Telescoped Synthesis of Thiazole Derivatives from β-Keto Esters and Thioureas Promoted by Tribromoisocyanuric Acid

A simple and efficient one-pot protocol has been developed for the synthesis of thiazole derivatives from readily available starting materials. Tribromoisocyanuric acid was successfully used for α-monohalogenation of β-keto esters in aqueous medium, which

DIFLUOROALKENE DERIVATIVE, PEST CONTROL AGENT CONTAINING THE SAME, AND INTERMEDIATE THEREFOR

A difluoroalkene derivative which is sufficiently effective in controlling various pests even when used in a small dose and is highly safe for crops, natural enemies to the pests, and animals; and an intermediate for the derivative. The difluoroalkene derivative is represented by the general formula: [I] wherein L1 and L2 are the same or different and each represents oxygen or sulfur; n is an integer of 2 to 8; and Q represents a 5- to 12-membered heterocyclic group having any desired heteroatom selected among nitrogen, oxygen, and sulfur.

Facile Synthesis of Aminothiazoles

The reaction of thioureas with ketones in the presence of N-bromosuccinimide furnishes 2-aminothiazoles.The method is quick, convenient and versatile.