98949-67-8Relevant academic research and scientific papers
Transition-metal-free visible Light-promoted photoredox oxidative dehydrogenative cyclization:expeditious approach to 1,2,4-thiadiazoles
Chen, Junmin,Sheng, Shouri,Xiong, Zhiqiang,Zhong, Qihao
supporting information, (2021/09/06)
A novel visible-light-catalyzed oxidative N-S bond formation for the synthesis of 3,5-disubstituted 1,2,4-thiadiazoles has been developed. This protocol features a metal-free approach, green oxidant, room temperature process, broad substrate scope, good functional group tolerance, excellent yields and a one-pot reaction without the isolation of the intermediates.
Co-Catalyzed Intramolecular S-N Bond Formation in Water for 1,2-Benzisothiazol-3(2H)-ones and 1,2,4-Thiadiazoles Synthesis
Yang, Liting,Song, Lijuan,Tang, Shanyu,Li, Longjia,Li, Heng,Yuan, Bingxin,Yang, Guanyu
, p. 1281 - 1285 (2019/01/14)
An efficient and versatile Co-catalyzed intramolecular S-N bond formation in water to synthesize 1,2-benzisothiazol-3(2H)-one and 1,2,4-thiadiazoles derivatives in good to excellent yields was developed. The transformation showed great tolerance with a broad range of substituents. The mother liquor was able to be recycled 6 times with minor loss in product yield.
Copper-catalyzed synthesis of 3-substituted-5-amino-1,2,4-thiadiazoles via intramolecular N-S bond formation
Kim, Ha-Young,Kwak, Se Hun,Lee, Gee-Hyung,Gong, Young-Dae
, p. 8737 - 8743 (2015/01/08)
A copper-catalyzed N-S bond formation was utilized to produce 3-substituted-5-amino-1,2,4-thiadiazoles from imidoyl thioureas obtained by reaction of amidine hydrochlorides with isothiocyanates. Moreover, the 1,2,4-thiadiazoles were generated through a on
