158654-83-2

Basic information

• Product Name: (S)-3-(Toluene-4-sulfonyloxy)-pyrrolidine-1-carboxylic acid benzyl ester
• Synonyms: (S)-3-(Toluene-4-sulfonyloxy)-pyrrolidine-1-carboxylic acid benzyl ester;(S)-Benzyl 3-(tosyloxy)pyrrolidine-1-carboxylate;benzyl (3S)-3-[(4-methylbenzenesulfonyl)oxy]pyrrolidine-1-carboxylate;1-Pyrrolidinecarboxylic acid, 3-[[(4-methylphenyl)sulfonyl]oxy]-, phenylmethyl ester, (3S)-
• CAS NO: 158654-83-2
• Molecular Formula: C₁₉H₂₁NO₅S
• Molecular Weight: 375.43874
• Mol File: 158654-83-2.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 537.9±50.0 °C(Predicted)
• Appearance: /
• Density: 1.33±0.1 g/cm3(Predicted)
• PKA: -3.63±0.40(Predicted)
• CAS DataBase Reference: (S)-3-(Toluene-4-sulfonyloxy)-pyrrolidine-1-carboxylic acid benzyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-3-(Toluene-4-sulfonyloxy)-pyrrolidine-1-carboxylic acid benzyl ester(158654-83-2)
• EPA Substance Registry System: (S)-3-(Toluene-4-sulfonyloxy)-pyrrolidine-1-carboxylic acid benzyl ester(158654-83-2)

Safety Data

• Hazardous Substances Data: 158654-83-2(Hazardous Substances Data)

Usage

General Description

The chemical compound "(S)-3-(Toluene-4-sulfonyloxy)-pyrrolidine-1-carboxylic acid benzyl ester" is a complex organic molecule that consists of a pyrrolidine ring with a toluene-4-sulfonyloxy group attached to it, as well as a benzyl ester group. The compound is a chiral molecule, indicated by the "(S)" prefix in its name, which means it has a specific three-dimensional arrangement of atoms. (S)-3-(Toluene-4-sulfonyloxy)-pyrrolidine-1-carboxylic acid benzyl ester may have potential applications in the field of organic synthesis and medicinal chemistry due to its unique structure and reactivity. Additional research and testing would be needed to fully understand its potential uses and properties.

Upstream product

• 100858-32-0 (S)-3-hydroxy-1-pyrrolidinecarboxylic acid phenylmethyl ester 
• 98-59-9 p-toluenesulfonyl chloride 
• 501-53-1 benzyl chloroformate 
• 13438-45-4 zinc(II) tosylate 
• 100858-33-1 (3R)-3-hydroxy-pyrrolidine-1-carboxylic acid benzyl ester 

Downstream Products

• 329012-80-8 3-cyanopyrrolidine-1-carboxylic acid benzyl ester 
• 192214-06-5 (R)-1-((benzyloxy)-carbonyl)pyrrolidine-3-carboxylic acid 

Relevant articles and documents

COMPOUNDS FOR TREATING HUNTINGTON'S DISEASE

The present description relates to compounds, forms, and pharmaceutical compositions thereof and methods of using such compounds, forms, or compositions thereof for treating or ameliorating Huntington's disease. In particular, the present description relates to substituted monocyclic heteroaryl compounds of Formula (I), Formula (II), or Formula (III), forms and pharmaceutical compositions thereof and methods of using such compounds, forms, or compositions thereof for treating or ameliorating Huntington's disease.

Synthesis and binding activity of endomorphin-1 analogues β-amino acids

Endomorphin-1 (Tyr-Pro-Trp-PheNH2) has been proposed as the most potent endogenous ligand of the μ-opioid receptors. In this paper, we describe the synthesis of some endomorphin-1 based tetrapeptides in which a residue of the sequence Tyr-Pro-Trp-PheNH2 is replaced by the corresponding β-isomer. These novel peptides showed different affinities for the opioid receptors labeled with [3H]-DAMGO in rat brain membranes, depending on the β-amino acid. In particular, the tetrapeptide containing β-Pro (Tyr-β-(R)-Pro-Trp-PheNH2) displayed a higher affinity than endogenous endomorphin-1, as revealed by their K(i) values (0.33 and 11.1 nM, respectively). (C) 2000 Elsevier Science Ltd.