158751-44-1Relevant academic research and scientific papers
Mechanism of alkaline cyclization of 2-(substituted benzamido)benzamides to 4-quinazolinones
Gardner,Kanagasooriam,Smyth,Williams
, p. 6245 - 6250 (1994)
The title amides cyclize rapidly to the corresponding quinazolin-4-ones in aqueous alkaline solution at 25°C; the pseudo-first-order rate constants fit the empirical equation k(obs) = k(max) [OH-]/(K(m) + [OH-] + [OH-]sup
