158751-55-4

Basic information

• Product Name: 2-methoxy-5-chloro-N-{5-[1-sulfonylamino-N-(methylaminocarbonyl)-2-methoxyphenyl]-ethyl}-benzamide
• Synonyms: 2-methoxy-5-chloro-N-{5-[1-sulfonylamino-N-(methylaminocarbonyl)-2-methoxyphenyl]-ethyl}-benzamide
• CAS NO: 158751-55-4
• Molecular Weight: 455.919
• Mol File: 158751-55-4.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 2-methoxy-5-chloro-N-{5-[1-sulfonylamino-N-(methylaminocarbonyl)-2-methoxyphenyl]-ethyl}-benzamide(CAS DataBase Reference)
• NIST Chemistry Reference: 2-methoxy-5-chloro-N-{5-[1-sulfonylamino-N-(methylaminocarbonyl)-2-methoxyphenyl]-ethyl}-benzamide(158751-55-4)
• EPA Substance Registry System: 2-methoxy-5-chloro-N-{5-[1-sulfonylamino-N-(methylaminocarbonyl)-2-methoxyphenyl]-ethyl}-benzamide(158751-55-4)

Safety Data

• Hazardous Substances Data: 158751-55-4(Hazardous Substances Data)

Upstream product

• 23170-77-6 N-methyltrichloroacetamide 
• 158751-78-1 2-methoxy-5-chloro-N-[5-(1-sulfonylamino-2-methoxyphenyl)-ethyl]-benzamide 
• 29568-33-0 2-methoxy-5-chlorobenzoyl chloride 
• 55-81-2 4-Methoxyphenethylamine 
• 158751-77-0 5-chloro-2-methoxy-N-(2-(4-methoxyphenyl)ethyl)benzamide 

Relevant articles and documents

Substituted benzenesulfonylureas and thioureas-process for their preparation and their use as pharmaceuticals

Benzenesulfonylureas and -thioureas of the formula I where R(1) in N or (fluoro)methyl, R(2) is H, Hal or (fluoro)(mercapto)alk(oxy)yl, E is O or S, Y is —[CR(3)2]n—, where R(3)=H or alkyl and n=1-4, X is H, Hal or alkyl and Z is Hal, NO2or alk(yl)oxy, are described. The compounds I are used for treatment of disturbances in cardiac rhythm and prevention of sudden cardiac death caused by arrhythmia, and can therefore be used as antiarrhythmics. They are particularly suitable for those cases where arrhythmias are a consequence of a narrowing of a coronary vessel, such as angina pectoris or acute cardiac infarction.

Substituted benzenesulfonylureas and -thioureas- process for their preparation and their use as pharmaceuticals

Benzenesulfonylureas and -thioureas of the formula I STR1 where R(1) is H or (fluoro)methyl, R(2) is H, Hal or (fluoro) (mercapto) alk (oxy) yl, E is O or S; Y is --[CR(3)2 ]n-, where R(3)=H or alkyl and n=1-4, X is H, Hal or alkyl and Z is Hal, NO2 or alk(yl)oxy, are described. The compounds I are used for treatment of disturbances in cardiac rhythm and prevention of sudden cardiac death caused by arrhythmia, and can therefore be used as antiarrhythmics. They are particularly suitable for those cases where arrhythmias are a consequence of a narrowing of a coronary vessel, such as angina pectoris or acute cardiac infarction.