1588428-28-7

Basic information

• Product Name: C₁₅H₉F₄NOS
• Synonyms: C₁₅H₉F₄NOS
• CAS NO: 1588428-28-7
• Molecular Weight: 327.302
• Mol File: 1588428-28-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₁₅H₉F₄NOS(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₅H₉F₄NOS(1588428-28-7)
• EPA Substance Registry System: C₁₅H₉F₄NOS(1588428-28-7)

Safety Data

• Hazardous Substances Data: 1588428-28-7(Hazardous Substances Data)

Upstream product

• 79419-73-1 (RS)-3-(4-fluorophenyl)-3-hydroxy-indolin-2-one 
• 282549-48-8 3-(4-fluorophenyl)indolin-2-one 
• 862907-06-0 tert-butyl 3-(4-fluorophenyl)-2-oxoindoline-1-carboxylate 
• 1567850-39-8 (S)-tert-butyl 3-(4-fluorophenyl)-3-(trifluoromethanesulfenyl)-2-oxoindoline-1-carboxylate 
• 352-13-6 4-flourophenylmagnesium bromide 
• 91-56-5 indole-2,3-dione 

Relevant articles and documents

In situ generation of electrophilic trifluoromethylthio reagents for enantioselective trifluoromethylthiolation of oxindoles

An organocatalytic asymmetric trifluoromethylthiolation reaction via in situ generation of active electrophilic trifluoromethylthio species involving trichloroisocyanuric acid and AgSCF3 as a practical and easily handled electrophilic SCF3 source for CSP 3-SCF3 bond formation was developed. Reactions with this one-pot version strategy occurred in good yields and excellent stereoselectivities to access enantiopure oxindoles bearing a SCF 3-substituted quaternary chiral center. The straightforward process described here makes use of simple starting materials and proceeds under mild conditions, which will be useful in medicinal chemistry and diversity-oriented syntheses.