159149-01-6Relevant academic research and scientific papers
Aminothiazole Derivatives. II. A Facile Synthesis of Condensed 4-Aminothiazole Derivatives using α-Bromolactams and Thioamides
Uchikawa, Osamu,Aono, Tetsuya
, p. 1545 - 1552 (2007/10/02)
The reaction of an α-bromolactam with a thioamide was found to give a cyclic 4-aminothiazole derivative.Novel heterocyclic compounds such as 4,5,6,7-tetrahydrothiazolopyridines 10, 5,6,7,8-tetrahydro-4H-thiazoloazepines 11, 4,5,6,7,8,9-hexahydrothiazoloazocine 12 and 9,10-dihydro-4H-thiazolobenzazepines 18 were thus prepared and the utility of this method in the construction of 4-aminothiazole-containing compounds was suggested.
