1591827-37-0

Basic information

• Product Name: 2,5-dichloro-3-hydroxybenzonitrile
• Synonyms: 2,5-dichloro-3-hydroxybenzonitrile
• CAS NO: 1591827-37-0
• Molecular Weight: 188.013
• Mol File: 1591827-37-0.mol

Chemical Properties

• CAS DataBase Reference: 2,5-dichloro-3-hydroxybenzonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 2,5-dichloro-3-hydroxybenzonitrile(1591827-37-0)
• EPA Substance Registry System: 2,5-dichloro-3-hydroxybenzonitrile(1591827-37-0)

Safety Data

• Hazardous Substances Data: 1591827-37-0(Hazardous Substances Data)

Upstream product

• 367-11-3 ortho-difluorobenzene 
• 2646-91-5 2,3-difluorobenzaldehyde 
• 21524-39-0 2,3-difluorobenzonitrile 
• 115661-37-5 2-amino-3-fluorobenzonitrile 

Downstream Products

• 1591827-36-9 2,5-dichloro-3-((6-oxo-4-(trifluoromethyl)-1,6-dihydropyrimidin-5-yl)oxy)benzonitrile 
• 1591824-10-0 2,5-dichloro-3-((6-oxo-1-((6-oxo-1,6-dihydropyridazin-3-yl)methyl)-4-(trifluoromethyl)-1,6-dihydropyrimidin-5-yl)oxy)benzonitrile 

Relevant articles and documents

PYRIDINONE DERIVATIVES AS SELECTIVE CYTOTOXIC AGENTS AGAINST HIV INFECTED CELLS

The present disclosure is directed to pyridinone derivatives of Formula I and their use for selectively killing HIV infected GAG-POL expressing cells without concomitant cytotoxicity to HIV nave cells, and for the treatment of infection by HIV, or for the treatment, prophylaxis or delay in the onset or progression of AIDS or AIDS Related Complex (ARC).

PYRIMIDONE DERIVATIVES AS SELECTIVE CYTOTOXIC AGENTS AGAINST HIV INFECTED CELLS

The present disclosure is directed to pyrimidone derivatives of Formula I and their use for selectively killing HIV infected GAG-POL expressing cells without concomitant cytotoxicity to HIV nave cells, and for the treatment or prophylaxis of infection by HIV, or for the treatment, prophylaxis or delay in the onset or progression of AIDS or AIDS Related Complex (ARC).